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dc.contributor.authorBortey-Sam, Nesta
dc.contributor.authorIkenaka, Yoshinori
dc.contributor.authorAkoto, Osei
dc.contributor.authorNakayama, Shouta, M.M.
dc.contributor.authorMarfo, Jemima T.
dc.date.accessioned2018-04-16T06:38:11Z
dc.date.available2018-04-16T06:38:11Z
dc.date.issued2018
dc.identifier.citationBortey-Sam, N. et al. 2018. Sex and site differences in urinary excretion of conjugated pyrene metabolites in the West African Shorthorn cattle. Journal of veterinary medical science, 80(2):375-381. [https://doi.org/10.1292/jvms.17-0410]en_US
dc.identifier.issn0916-7250
dc.identifier.issn1347-7439 (Online)
dc.identifier.urihttp://hdl.handle.net/10394/26703
dc.identifier.urihttps://doi.org/10.1292/jvms.17-0410
dc.identifier.urihttps://www.jstage.jst.go.jp/article/jvms/80/2/80_17-0410/_pdf/-char/en
dc.description.abstractIndustrialization, economic and population growth rates in Ghana have increased the release of contaminants including polycyclic aromatic hydrocarbons (PAHs) into the environment through which humans and animals are exposed. Cattle is reported to be exposed to high levels of PAHs through feed and inhalation. Once exposed, PAHs are metabolized and excreted in urine, feces or bile. In a previous study, cattle in Ghana was reported to excrete high levels of 1-hydroxypyrene (1-OHPyr) due to high exposure to the parent compound, pyrene. 1-OHPyr is further metabolized to glucuronide and sulfate conjugates. Thus, the aim of this study was to investigate the sex and site differences in urinary excretion of conjugated pyrene metabolites using cattle urine collected from rural and urban sites of the Ashanti region, Ghana. From the results, geometric mean concentration adjusted by specific gravity indicated that 1-OHPyreneGlucuronide (PyG) was the most abundant conjugate followed by PyrenediolSulfate (M3). The sum of conjugated pyrene metabolites and sum of both conjugated and deconjugated pyrene metabolites correlated significantly with PyG, PydiolSulfate (M2) and PydiolSulfate (M3). The study revealed no significant difference in urinary excretion of conjugated pyrene metabolites between rural and urban sites. This indicated that similar to urban sites, cattle in rural sites were exposed to high levels of pyrene. There was no significant difference in urinary concentrations of conjugated pyrene metabolites between sexesen_US
dc.language.isoenen_US
dc.publisherJapanese Society of Veterinary Scienceen_US
dc.subjectCattleen_US
dc.subjectKumasien_US
dc.subjectMetabolitesen_US
dc.subjectPAHsen_US
dc.subjectUrineen_US
dc.titleSex and site differences in urinary excretion of conjugated pyrene metabolites in the West African Shorthorn cattleen_US
dc.typeArticleen_US
dc.contributor.researchID27878368 - Ikenaka, Yoshinori


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