A quick and painless reminder: the pharmacotherapy of rheumatoid arthritis in primary practice
Abstract
Rheumatoid arthritis, an auto-immune disorder, is characterised by chronic inflammation of the joints, synovial hyperplasia and
bone erosion. These pathological features are promoted by a synovial microenvironment featuring B-cell and T-cell infiltrate,
synovial fibroblasts and an intricate network of pro-inflammatory cellular messengers – prominent molecular role-players that
represent critical targets in the pharmacotherapy of the disease. This review offers a brief overview of the etiopathology of
rheumatoid arthritis while focussing on the practical aspects of methotrexate and glucocorticoid use that are of relevance for
primary practice
URI
http://hdl.handle.net/10394/31355https://safpj.co.za/index.php/safpj/article/view/4839
https://doi.org/10.4102/safp.v60i2.4839
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