Stress and neurovascular coupling: a red flag? The SABPA study
Date
2019Author
Malan, Leoné
Hamer, Mark
Von Känel, Roland
Smith, Wayne
Steyn, Faans
Malan, Nicolaas
Metadata
Show full item recordAbstract
Neuronal hyperactivity mediates communication between neurons and blood vessels (neurovascular coupling) and increases susceptibility for retinal ganglion
cells functionality. Contrastingly, monoamine depletion and hypo-activity of cortisol reflected major depression, which may also
disturb neurovascular coupling. Hence our objectives were to assess: 1) trajectories of two major stress hormones (norepinephrine
and cortisol) over 3 yrs; and determine 2) associations between the
retinal vasculature and stress hormone changes and responses
during flicker-light-induced-provocation (FLIP)
URI
http://hdl.handle.net/10394/32361https://www.karger.com/Article/Pdf/499516
https://doi.org/10.1159/000499516