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Erythrocyte membrane fatty acids in patients with multiple sclerosis

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dc.contributor.author Smuts, Cornelius en_US
dc.contributor.author Hon, G M
dc.contributor.author Hassan, M S
dc.contributor.author Van Rensburg, S J
dc.contributor.author Abel, S
dc.contributor.author Marais, D W
dc.contributor.author Van Jaarsveld, P
dc.contributor.author Henning, F
dc.contributor.author Erasmus, R T
dc.contributor.author Matsha, T
dc.date.accessioned 2010-08-04T15:36:01Z
dc.date.available 2010-08-04T15:36:01Z
dc.date.issued 2009 en_US
dc.identifier.citation SMUTS, C., HON, G.M., HASSAN, M.S., VAN RENSBURG, S.J., ABEL, S., MARAIS, D.W., VAN JAARVELD, P., HENNING, F., ERASMUS, R.T. & MATSHA, T. 2009. Erythrocyte membrane fatty acids in patients with multiple sclerosis. Multiple Sclerosis, 15(6):759-62, Jun. [http://msj.sagepub.com/] en_US
dc.identifier.issn 1352-4585
dc.identifier.issn 1477-0970 (Online)
dc.identifier.uri http://hdl.handle.net/10394/3336
dc.description.abstract Background Reports on fatty acids levels in multiple sclerosis remain inconclusive. Objective To determine the erythrocyte membrane fatty acid levels in multiple sclerosis patients and correlate with Kurtzke Expanded Disability Status Scale. Methods Fatty acid composition of 31 multiple sclerosis and 30 control individuals were measured by gas chromatography. Results The membrane phosphatidylcholine C20:4n – 6 concentration was lower in the multiple sclerosis patients when compared to that of the control group, P = 0.04 and it correlated inversely with the EDSS and FSS. Conclusion Decrease in C20:4n – 6 in the erythrocyte membrane could be an indication of depleted plasma stores, and a eflection of disease severity. Multiple Sclerosis 2009; 15: 759–762. http://msj.sagepub.com
dc.publisher SAGE Publications
dc.title Erythrocyte membrane fatty acids in patients with multiple sclerosis en_US


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