An UV spectrophotometric method was developed for the quantitative determination of nevirapine in water, methanol and 0.1 N HCl. It was found that qualitative determination is also possible, due to a peak-shift observed with 0.1 N HCl. The solubility at 37°C, for both the anhydrous and Hemihydrated forms of nevirapine, was determined in each of the three solvents.
An UV spectrophotometric method was developed for the quantitative determination of nevirapine in water, methanol and 0.1 N HCl. It was found that qualitative determination is also possible, due to a peak-shift observed with 0.1 N HCl. The solubility at 37°C, for both the anhydrous and Hemihydrated forms of nevirapine, was determined in each of the three solvents.