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UV Spectrophotometric method for the identification and solubility determination of nevirapine

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dc.contributor.author Wessels, Johanna en_US
dc.contributor.author Stieger, Nicole en_US
dc.contributor.author Liebenberg, Wilna en_US
dc.date.accessioned 2010-08-04T15:36:13Z
dc.date.available 2010-08-04T15:36:13Z
dc.date.issued 2009 en_US
dc.identifier.citation WESSELS, J., STIEGER, N., & LIEBENBERG, W. 2009. UV Spectrophotometric method for the identification and solubility determination of nevirapine. Pharmazie, 64(10):690-691, Oct. [http://www.govi.de/pharmazie.htm] [http://www.ncbi.nlm.nih.gov/pubmed] en_US
dc.identifier.issn 0031-7144
dc.identifier.issn 0031-7144 (Online)
dc.identifier.uri http://hdl.handle.net/10394/3405
dc.description.abstract An UV spectrophotometric method was developed for the quantitative determination of nevirapine in water, methanol and 0.1 N HCl. It was found that qualitative determination is also possible, due to a peak-shift observed with 0.1 N HCl. The solubility at 37°C, for both the anhydrous and Hemihydrated forms of nevirapine, was determined in each of the three solvents.
dc.description.abstract An UV spectrophotometric method was developed for the quantitative determination of nevirapine in water, methanol and 0.1 N HCl. It was found that qualitative determination is also possible, due to a peak-shift observed with 0.1 N HCl. The solubility at 37°C, for both the anhydrous and Hemihydrated forms of nevirapine, was determined in each of the three solvents.
dc.description.uri http://dx.doi.org/10.1691/ph.2009.9163
dc.publisher PubMed
dc.title UV Spectrophotometric method for the identification and solubility determination of nevirapine en_US


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