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dc.contributor.authorMuraina, Issa A.
dc.contributor.authorOnyiche, ThankGod E.
dc.contributor.authorGotep, Jurbe G.
dc.contributor.authorTanko, James T.
dc.contributor.authorAladelokun, Oladimeji B.
dc.date.accessioned2020-03-26T06:31:57Z
dc.date.available2020-03-26T06:31:57Z
dc.date.issued2020
dc.identifier.citationMuraina, I.A. et al. 2020. Anticoccidial effects of Khaya senegalensis aqueous stem bark extract on broiler chickens experimentally infected with Eimeria species. Tropical animal health and production, 52:1249-1255. [https://doi.org/10.1007/s11250-019-02125-4]en_US
dc.identifier.issn0049-4747
dc.identifier.issn1573-7438 (Online)
dc.identifier.urihttp://hdl.handle.net/10394/34441
dc.identifier.urihttps://link.springer.com/article/10.1007/s11250-019-02125-4
dc.identifier.urihttps://doi.org/10.1007/s11250-019-02125-4
dc.description.abstractGraded concentrations (200, 400 and 800 mg/kg) of the aqueous stem bark extract of Khaya senegalensis was evaluated for its therapeutic efficacy against experimentally induced coccidiosis in broiler chicken. The phytochemical analysis shows the presence of tannins, saponins, cardiac glycosides and steroids. There was significant reduction in oocyst count across the groups in a graded dose manner with 800 mg/kg being the most efficacious dose. There was also weight gain across the treatment groups with immuno-modulatory and erythropoetic activities observed. Also, a significant (p < 0.05) graded dose-dependent reduction in the oocyst count in the treatment groups. A significant (p < 0.05) increase in mean weight gain was also recorded across the experimental groups except the negative control. The haematology also showed a dose-dependent increase in red blood cells, haemoglobin and packed cell volume of the treatment groups. The extract had no significant difference (p > 0.05) on the white blood cells, but a slight decrease in the white blood cells and heterophil counts was observed at 400 mg/kg. Furthermore, the aspartate amino transaminase level showed a significant difference (p < 0.05). Fluctuating levels of other serum biochemical parameters such as total protein, albumin and potassium were observed. No significant difference (p > 0.05) in the sodium concentration was observed. In addition, oxidative stress biomarkers such as catalase significantly increased (p < 0.05) in all the experimental groups in addition to the concomitant increase in reduced gluthathione (GSH) and superoxide dismutase (SOD) levels. Conclusively, the aqueous extract of K. senegalensis was effective in the management of coccidiosis thus supporting its folkloric useen_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.subjectEimeriaen_US
dc.subjectKhaya senagalensisen_US
dc.subjectAnticoccidialen_US
dc.subjectAntioxidanten_US
dc.subjectBroiler chickenen_US
dc.titleAnticoccidial effects of Khaya senegalensis aqueous stem bark extract on broiler chickens experimentally infected with Eimeria speciesen_US
dc.typeArticleen_US
dc.contributor.researchID29228409 - Onyiche, ThankGod E.


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