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The synthesis and evaluation of caffeine analogues as inhibitors of monoamine oxidase B and antagonists of the adenosine A₂A receptor / by Judey Pretorius

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dc.contributor.author Pretorius, Judey
dc.date.accessioned 2011-04-08T13:26:59Z
dc.date.available 2011-04-08T13:26:59Z
dc.date.issued 2008
dc.identifier.uri http://hdl.handle.net/10394/4127
dc.description Thesis (Ph.D. (Pharmaceutical Chemistry))--North-West University, Potchefstroom Campus, 2009.
dc.description.abstract The adenosine A2A receptor has emerged as an attractive target for the treatment of Parkinson's disease (PD). Evidence suggests that antagonists of the A2A receptor (A2A antagonists) partially alleviate the symptoms of PD, prevent the development of motor complications and may also slow the underlying neurodegenerative process. It was recently reported that several members of the (E)-8-styrylcaffeine class of A2A antagonists also are potent inhibitors of monoamine oxidase B (MAO-B).
dc.publisher North-West University
dc.title The synthesis and evaluation of caffeine analogues as inhibitors of monoamine oxidase B and antagonists of the adenosine A₂A receptor / by Judey Pretorius en
dc.type Thesis en
dc.description.thesistype Doctoral


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    This collection contains the original digitized versions of research conducted at the North-West University (Potchefstroom Campus)

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