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dc.contributor.authorBadenhorst, Hendrik Louisen_US
dc.date.accessioned2011-09-06T09:52:56Z
dc.date.available2011-09-06T09:52:56Z
dc.date.issued2010en_US
dc.identifier.urihttp://hdl.handle.net/10394/4653
dc.descriptionThesis (M.Sc. (Occupational Hygiene))--North-West University, Potchefstroom Campus, 2011.
dc.description.abstractTuberculosis is a disease that has a detrimental effect on the economic growth of South Africa. The country’s TB mortality rate is amongst the highest in the world, and the worst affected industry is mining. Effective environmental controls of tuberculosis in mining areas remain a challenge, mainly because there is a lack of quantitative data to guide the implementation of these controls. No occupational exposure limits exist for bio–aerosols, particularly Mycobacterium tuberculosis. This makes it difficult to distinguish between high– and low risk areas. It is believed that a single inhaled M. tuberculosis particle can cause the tuberculosis disease, and as this disease can deteriorate all major systems of the body, great care should be taken in the classification of an area. Aim: This study aimed to quantify the environmental presence of the M. tuberculosis bacilli in various occupational settings of a platinum mine. Method: The monitored areas are all structures above ground, and include high TB risk areas, such as the hospital TB Ward, and low TB risk areas, such as an office area. Personal monitoring of the staff in high TB risk areas has also been conducted. Monitoring was done via the PTFE filter sampling method and the SKC Bio–Sampler impinger method. The results of these two methods were compared to determine which method is more effective. The environmental variables, such as carbon dioxide and -monoxide levels, temperature (both ambient and wet– bulb), and relative humidity, were also monitored in order to identify any possible correlations between these variables and the levels of ambient TB particles. The effectiveness of the Ultraviolet Germicidal Irradiation (UVGI) system, which is in place in some of the monitored areas, was also indirectly assessed, i.e. to see if there are any M. tuberculosis particles present in an area that makes use of an UVGI system. The PCR analytical method was used to quantify the number of M. tuberculosis bacilli sampled, and the results were statistically analysed. Results: M. tuberculosis was found to be present in the office area, the laundry room, the hospital’s waiting area, the training facility, the dining room, and the mobile clinic. No M. tuberculosis particles were found in the hospital’s TB Ward and the change houses of the mine. The results showed that the PTFE filter method had a greater efficiency than the SKC Bio– Sampler in monitoring environmental M. tuberculosis particles, as the PTFE filter method yielded positive samples where the SKC Bio–Sampler did not. There is a practical significant difference between the two methods. No viable correlations between the environmental variables and M. tuberculosis prevalence were established due to the low number of samples taken. Conclusion: It seems that the effectiveness of a UVGI system is dependent on the number of people crowded into that specific area and the ventilation thereof. A UVGI system is only a precautionary measure and not a solution. There are too many factors that still need better understanding before the risk of contracting environmental TB in high risk areas of a mine can be determined. The high risk areas seem to be occupational settings that have poor ventilation, but accommodate a large number of people. The highest risk of TB infection remains close contact with infected individuals, as the results of the employee monitoring testified.en_US
dc.publisherNorth-West University
dc.subjectTuberculosisen_US
dc.subjectTransmissionen_US
dc.subjectEnvironmenten_US
dc.subjectMine settingen_US
dc.subjectOvercrowdingen_US
dc.subjectVentilationen_US
dc.subjectMulti-drug resistant tuberculosisen_US
dc.subjectTuberkuloseen_US
dc.subjectOordragen_US
dc.subjectOmgewingen_US
dc.subjectMyn plasingen_US
dc.subjectOorbevolkingen_US
dc.subjectVentilasieen_US
dc.subjectVeelvuldige medisinale weerstandbiedende tuberkuloseen_US
dc.titleThe environmental monitoring and quantification of M. tuberculosis occupational exposure risk in various occupational settings in a platinum mine / H.L. Badenhorsten_US
dc.typeThesisen_US
dc.description.thesistypeMastersen_US


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    This collection contains the original digitized versions of research conducted at the North-West University (Potchefstroom Campus)

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