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dc.contributor.authorGouws, Chrisnaen_US
dc.date.accessioned2012-08-23T13:19:56Z
dc.date.available2012-08-23T13:19:56Z
dc.date.issued2011en_US
dc.identifier.urihttp://hdl.handle.net/10394/7010
dc.descriptionThesis (Ph.D. (Biochemistry))--North-West University, Potchefstroom Campus, 2012.
dc.description.abstractOccupational risk management can be a catalyst in generating superior returns for all stakeholders on a sustainable basis. A number of companies in South Africa have implemented Cardinal Rules of Safety adopted from international companies to ensure the safety of their employees. The purpose of this study was to measure the impact of the cardinal rules on employee safety behaviour implemented at power stations in Mpumalanga. The empirical study was done by using a questionnaire as measuring instrument. The questionnaire was developed from a literature review and contains questions and items relevant to the initial research problem. The questionnaire comprised of five–point Likert scale type questions.The convenience sampling method was applied identifying 90 participants at three different power stations in Mpumalanga taking part in the study. Statistical analysis was performed by the Statistical Consulting Service of the North–West University using SPSS. Cronbach’s alpha co–efficients was used to determine the reliability of the factors. Descriptive statistics (Mean, standard, deviation, were used in the compiling of the profile of the results. While Spearman’s rho correlation coefficient was calculated to identify practically significant associations between variables and factors The research findings suggest that there is practical significant correlation between the factors that were measured. The opinion given by respondents suggests that cardinal rules of safety were implemented, given all the necessary support by management and enforced throughout the organisation.en_US
dc.publisherNorth-West University
dc.subjectHereditary tyrosinemia type 1en_US
dc.subjectHepatocellular carcinomaen_US
dc.subjectDNA methylationen_US
dc.subjectDNA alkylationen_US
dc.subjectReactive oxygen speciesen_US
dc.subjectOxidative stressen_US
dc.subjectOorerflike tirosinemie tipe 1en_US
dc.subjectHepatosellulêre karsinoomen_US
dc.subjectDNS-metileringen_US
dc.subjectDNS-alkileringen_US
dc.subjectReaktiewe suurstof spesiesen_US
dc.subjectOksidatiewe stresen_US
dc.titleTyrosinemia type I as a model for studying epigenetic events in the aetiology of metabolic disease associated hepatocarcinomaen
dc.typeThesisen_US
dc.description.thesistypeDoctoralen_US


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    This collection contains the original digitized versions of research conducted at the North-West University (Potchefstroom Campus)

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