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The design and development of a stented tissue mitral and aortic heart valve replacement for human implantation

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dc.contributor.author Legg, Murray Christopher
dc.contributor.author Mathews, Edward Henry
dc.contributor.author Pelzer, Ruaan
dc.date.accessioned 2012-09-18T09:55:26Z
dc.date.available 2012-09-18T09:55:26Z
dc.date.issued 2012
dc.identifier.citation Legg, M.C. et al. 2012. The design and development of a stented tissue mitral and aortic heart valve replacement for human implantation. Cardiovascular journal of Africa, 23(3):126-130. [http://www.cvja.co.za/information.php] en_US
dc.identifier.issn 1995-1892
dc.identifier.issn 1996-3467 (Online)
dc.identifier.uri http://hdl.handle.net/10394/7396
dc.description CVJA is the official journal of the PASCAR (Pan African Society of Cardiology) en_US
dc.description.abstract A study was conducted into the development of a mitral and aortic heart valve replacement that caters for patients having suffered valve damage due to stenosis or rheumatic fever. The appeal of the valve is that it is constituted from a solid frame housing pericardial tissue leaflets, and allows the patient freedom from post-operative blood-thinning medication. The valve is designed to appeal to patients in developing areas of the world, as it features a clip-in mechanism to secure the valve assembly into the sewing ring, which is stitched in independently of the frame and leaflets. Re-operative valve replacement would then be made possible when the pericardial leaflets began to calcify. Novel aspects of the design added value to the science of heart valve replacements, through the use of sintered chrome cobalt in the valve components, the insights gained into mechanical testing of pericardium, and the patient benefits offered by the complete design. Further work is planned to fatigue test the assembly, undergo animal trials and make the valve available for commercial use. en_US
dc.description.uri http://dx.doi.org/10.5830/CVJ-21.059
dc.language.iso en en_US
dc.publisher Clinics Cardive en_US
dc.subject Aortic valve replacement en_US
dc.subject mitral valve replcement en_US
dc.subject tissue valve en_US
dc.title The design and development of a stented tissue mitral and aortic heart valve replacement for human implantation en_US
dc.type Article en_US


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