Smoking and vascular dysfunction in Africans and caucasians from South Africa

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dc.contributor.author Schutte, Aletta Elisabeth
dc.contributor.author Van Rooyen, Johannes Marthinus
dc.contributor.author Zatu, Mandlenkosi Caswell
dc.date.accessioned 2012-09-18T10:41:38Z
dc.date.available 2012-09-18T10:41:38Z
dc.date.issued 2011
dc.identifier.citation Zatu, M.C. et al.2011. Smoking and vascular dysfunction in Africans and saucasians from South Africa. Cardiovascular journal of Africa, 22(1):18-24. [http://www.cvja.co.za/information.php] en_US
dc.identifier.issn 1995-1892
dc.identifier.issn 1996-3467 (Online)
dc.identifier.uri http://hdl.handle.net/10394/7397
dc.description CVJA is the official journal of the PASCAR (Pan African Society of Cardiology) en_US
dc.description.abstract Background: Smoking is an important modifiable risk factor for cardiovascular disease, with limited research having been done in Africans. We aimed to determine the association between smoking and measurements of vascular function in Africans and Caucasians. Methods: We determined anthropometric and cardiovascular variables, serum cotinine and C-reactive protein (CRP) in African and Caucasian participants from South Africa (n = 630). Results: Africans had significantly lower body mass index (BMI), higher blood pressure and lower socio-economic status (SES) than Caucasians. Only African smokers showed increased arterial stiffness and a significant correlation between smoking and arterial stiffness. African smokers had increased and Caucasian smokers decreased high-density lipoprotein cholesterol (HDL-C) than the non-smokers. After adjusting for confounders, smoking showed few correlations, mainly with heart rate and CRP. In Africans, smoking also correlated positively with HDL-C, with the opposite result in Caucasians. Conclusion: African smokers had significantly increased arterial stiffness, which was not found in Caucasian smokers. Africans generally demonstrated more associations between smoking and cardiovascular dysfunction than Caucasians. en_US
dc.language.iso en en_US
dc.publisher Clinics Cardive en_US
dc.subject Smoking en_US
dc.subject vascular dysfunction en_US
dc.subject socio-economic status en_US
dc.subject ethnicity en_US
dc.subject Africans en_US
dc.subject caucasians en_US
dc.title Smoking and vascular dysfunction in Africans and caucasians from South Africa en_US
dc.type Article en_US

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