Browsing by Title
Now showing items 21-40 of 35682
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2-Acetylphenol analogs as potent reversible monoamine oxidase inhibitors
(Dove Press, 2015)Based on a previous report that substituted 2-acetylphenols may be promising leads for the design of novel monoamine oxidase (MAO) inhibitors, a series of C5-substituted 2-acetylphenol analogs (15) and related compounds ... -
2-Aminopyrimidines as dual adenosine A1/A2A antagonists
(Elsevier, 2015)In this study thirteen 2-aminopyrimidine derivatives were synthesised and screened as potential antagonists of adenosine A1 and A2A receptors in order to further investigate the structure activity relationships of this ... -
2-Benzylidene-1-indanone analogues as dual adenosine A1/A2a receptor antagonists for the potential treatment of neurological conditions
(Thieme, 2019)Previous studies explored 2-benzylidine-1-tetralone derivatives as innovative adenosine A1 and A2A receptor antagonists for alternative non-dopaminergic treatment of Parkinson’s disease. This study’s aim is to investigate ... -
2-Benzylidene-1-indanone derivatives as inhibitors of monoamine oxidase
(Elsevier, 2016)In the present study, a series of twenty-two 2-benzylidene-1-indanone derivatives were synthesised and evaluated as inhibitors of recombinant human monoamine oxidase (MAO) A and B. The 2-benzylidene-1-indanone derivatives ... -
A 2-Decade Appraisal of African Nursing Scholarship: 1986-2006
(Wiley-Blackwell, 2009)This paper is a description of a study about articles published about nursing in Africa from 1986 to 2006. METHODS: An exhaustive database search of articles written by nurses or articles related to nursing in Africa was ... -
(2-Ethyl-2-oxazoline- kN)bis(N-ethyl-N-phenyldithiocarbamato- k2S,S')cadmium
(International Union of Crystallography, 2012)In the title compound, [Cd(C9H10NS2)2(C5H9NO)], the CdII atom is five-coordinated in a distorted square-pyramidal geometry by four S atoms from two chelating N-ethyl-N- phenyl dithiocarbamate ligands and one N atom from a ... -
2-Heteroarylidene-1-indanone derivatives as inhibitors of monoamine oxidase
(Elsevier, 2016)In the present study a series of fifteen 2-heteroarylidene-1-indanone derivatives were synthesised and evaluated as inhibitors of recombinant human monoamine oxidase (MAO) A and B. These compounds are structurally related ... -
20 Years of air-water gas exchange observations for pesticides in the Western Arctic Ocean
(ACS, 2015)The Arctic has been contaminated by legacy organochlorine pesticides (OCPs) and currently used pesticides (CUPs) through atmospheric transport and oceanic currents. Here we report the time trends and air−water exchange ... -
2007 - Opvoeder-tot-leerder seksuele teistering in sekondere skole
(Suid-Afrikaanse Akademie vir Wetenskap en Kuns/South African Academy of Science and Arts, 2009)The Promotion of Equality and Prevention of Unfair Discrimination Act (SA 2000) describes sexual harassment as unwelcome behaviour relating to sex, gender or sexual orientation, or which is related to a person's membership ... -
The 2009 South African elections: Implications for the provinces
(Published by the Department of History, University of the Free State, 2010)The 2009 South African elections were somewhat different in terms of the positioning of the ruling party and the nature of the opposition. Against this background the meaning and implications (democratic meaningfulness) ... -
The 2010 very high energy γ-ray flare and 10 years of multi-wavelength observations of M 87
(IOP Publishing, 2012)The giant radio galaxy M 87 with its proximity (16 Mpc), famous jet, and very massive black hole ((3 – 6) × 109 M☉) provides a unique opportunity to investigate the origin of very high energy (VHE; E > 100 GeV) γ-ray ... -
The 2011 local elections campaigns in the Tlokwe municipality, North-West Province: enhancing participatory governance?
(University of the Free State?, 2011)The South African Local Government Municipal Systems Act (Act 32 of 2000) requires participatory governance. Although this Act is not concerned with electoral participation in the first instance, it is argued that it also ... -
The 2011 local government elections: considering policy and legislative responses to local government challenges
(Unisa Press, 2012)Within the context of the 2011 local government elections (hereafter the 2011 elections), this article explores the correlation between the main issues raised by political parties as local government challenges and ... -
The 2012 acid mine drainage (AMD) crisis in Carolina's municipal water supply
(Taylor & Francis & UNISA Press, 2014)There are growing concerns in South Africa about the threat that acid mine drainage (AMD) poses to local natural water resources in many of the country's mining areas. Since the beginning of the 21st century, the toxic ... -
The 2012 flare of PG 1553+113 seen with H.E.S.S. and Fermi-LAT
(IOP Publishing, 2015)Very high energy (VHE, E > 100 GeV) γ-ray flaring activity of the high-frequency peaked BL Lac object PG 1553+113 has been detected by the H.E.S.S. telescopes. The flux of the source increased by a factor of 3 during the ... -
The 2014 TeV γ-ray flare of Mrk 501 seen with H.E.S.S.: temporal and spectral constraints on Lorentz invariance violation
(IOP Publishing, 2019)The blazar Mrk 501 (z = 0.034) was observed at very-high-energy (VHE, E gsim 100 GeV) gamma-ray wavelengths during a bright flare on the night of 2014 June 23–24 (MJD 56832) with the H.E.S.S. phase-II array of Cherenkov ... -
The 2019 review of IPBES and future priorities: reaching beyond assessment to enhance policy impact
(Taylor & Francis, 2020)The Intergovernmental Science–Policy Platform on Biodiversity and Ecosystem Services (IPBES) is an independent scientific body focused on assessing the state of the world’s ecosystem services and biodiversity. IPBES members ... -
2020 International Society of Hypertension global hypertension practice guidelines
(AHA, 2020)Context and Purpose of This Guideline Statement of Remit To align with its mission to reduce the global burden of raised blood pressure (BP), the International Society of Hypertension (ISH) has developed worldwide ...
