Browsing by Title
Now showing items 21711-21730 of 35418
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A metabolomics investigation of tuberculous meningitis in infants and children
(North-West University (South Africa), 2016)This thesis, titled: ‘A metabolomics investigation of Tuberculous Meningitis in infants and children’, deals with tuberculous meningitis (TBM), the most severe complication of tuberculosis (TB) and major pandemic of our ... -
A metabolomics investigation on experimental interventions of acute alcohol consumption
(North-West University, 2018)This thesis, titled: "A metabolomics investigation on experimental interventions of acute alcohol consumption", deals with a current topic of global interest, namely, alcohol use and abuse. Alcohol abuse is associated with ... -
The metabolomics of acute alcohol abuse
(North-West University, 2010)Alcohol is a substance used and abused by many individuals. The metabolic perturbations caused by excessive alcohol consumption are widespread throughout the human body. One of the primary consequences of alcohol abuse, ... -
Metabolomics of bilharziasis
(North-West University, 2012)Bilharziasis, a disease that is a major health problem in tropical and subtropical countries, is caused by worms of the genus Schistosoma. The main disease–causing species are S. haematobium, S. mansoni and S. japonicum. ... -
Metabolomics of colistin methanesulfonate treated Mycobacterium tuberculosis
(Elsevier, 2018)Over the past 5 years, there has been a renewed interest in finding new compounds with anti-TB action. Colistin methanesulfonate or polymyxin E, is a possible anti-TB drug candidate, which may in future be used either alone ... -
Metabolomics of hypertension in South Africans : the SABPA Study
(North-West University (South Africa), 2015)There has been growing concern in recent years about the alarmingly high prevalence and severity of hypertension and other cardiovascular diseases in individuals from newly (or recently) westernised countries such as ... -
Metabolomics of mitochondrial disease
(Elsevier, 2017)Mitochondrial disease (MD) diagnostics and disease progression investigations have traditionally relied very little on metabolic data, due to a lack of biomarker sensitivity and specificity. The recent drive to find novel, ... -
Metabolomics of Ndufs4−/− skeletal muscle: adaptive mechanisms converge at the ubiquinone-cycle
(Elsevier, 2019)Leigh syndrome is one of the most common childhood-onset neurometabolic disorders resulting from a primary oxidative phosphorylation dysfunction and affecting mostly brain tissues. Ndufs4−/− mice have been widely used to ... -
Metabolomics of urinary organic acids in respiratory chain deficiencies in children
(Springer, 2012)Metabolomic analysis of the urinary organic acids from 39 selected children with defined respiratory chain deficiencies (RCDs) was performed using untargeted gas chromatography–mass spectrometry, revealing the presence ... -
Metabolomics reveals the depletion of intracellular metabolites in HepG2 cells after treatment with gold nanoparticles
(Taylor & Francis, 2018)Studies on the safety of gold nanoparticles (GNPs) are plentiful due to their successful application in drug delivery and treatment of diseases in trials. Cytotoxicity caused by GNPs has been studied on the physiological ... -
A metabolomics study of selected perturbations of normal human metabolism
(North-West University, 2010)Metabolism is an integrated network of biochemical pathways involving a series of enzymecatalysed anabolic or catabolic reactions in cells. Metabolites are chemical compounds that are involved in or are products ... -
Metabolomics variable selection and classification in the presence of observations below the detection limit using an extension of ERp
(BioMed Central, 2017)Background ERp is a variable selection and classification method for metabolomics data. ERp uses minimized classification error rates, based on data from a control and experimental group, to test the null hypothesis of ... -
Metabotropic and ionotropic glutamate receptors as neurobiological targets in anxiety and stress-related disorders: focus on pharmacology and preclinical translational models
(Elsevier, 2012)Anxiety disorders are amongst the most common and disabling of psychiatric illnesses and have severe health and socio-economic implications. Despite the availability of a number of treatment options there is still a strong ... -
Metacognition within physical sciences classrooms in Two KwaZulu-Natal Districts
(North-West University (South Africa), 2019)For South Africa to become a leader in science and technology, it needs to produce many world-class scientists. South African education falls short of that goal because most learners are indigenous learners and those ... -
A metacognitive approach to pair programming: influence on metacognitive awareness
(University of Almeria, 2014)Introduction. The research focused on metacognition in a collaborative learning setting. Based on a comprehensive literature study the researchers designed a metacognitive teachinglearning strategy for pair programmers. ... -
A metacognitive approach to pair programming: influence on metacognitve awareness
(University of Almeria, 2014)Introduction. The research focused on metacognition in a collaborative learning setting. Based on a comprehensive literature study the researchers designed a metacognitive teaching-learning strategy for pair programmers. ... -
Metacognitive locale : a design-based theory of students' metacognitive language and networking in mathematics
(2015)The purpose of this study was to design a local theory explaining the relationship between metacognitive language and networks as constructs of a local instructional theory in the context of a fourth-year intermediate ... -
Metaforiese funksies in die rolmodelskap van die Christenonderwyser: 'n pastorale studie
(North-West University, 2010)The objective of this practical theological study was to explore to what extent a pastoral accentuation of Christian teachers as role models can result in a new perspective on the teacher-learner relationship in the South ... -
Metagenomic analyses of bacterial endophytes associated with the phyllosphere of a Bt maize cultivar and its isogenic parental line from South Africa
(Springer, 2017)Genetic modification of maize with Bacillus thuringiensis (Bt) cry proteins may predispose shifts in the bacterial endophytes’ community associated with maize shoots. In this study, the diversity of bacterial endophytes ... -
Metagenomic analysis of 16S sequences of nitrifying bacteria and archaea inhabiting maize rhizosphere
(North-West University (South Africa), 2022)The global nitrogen cycle has been disrupted, mainly as a result of nitrogen-based synthetic fertilizers and other agrochemicals used in plant cultivation. Microbial inoculation is fast becoming an environmentally friendly ...
