Browsing by Title

A novel reversed-phase LC method for quantitative detection of azithromycin in bulk drug and tablet formulations in various aqueous media

Odendaal, R.W.; Liebenberg, W.; Aucamp, M.E. (Avoxa, 2012)

A novel reversed-phase HPLC method with UV-detection for separation, identification and quantification of azithromycin (AZH) was developed. The method was validated for the purpose of quantifying AZH in stability, ...

A novel RP-HPLC method for the detection and quantification of clarithromycin or spiramycin in bulk drug samples and dosage forms

Katsidzira, Runako Masline; Wessels, Anita; Aucamp, Marique (Innovare Academic Sciences, 2016)

Objective: This study was aimed at developing an HPLC method that would be suitable and sufficiently robust to analyze clarithromycin or spiramycin from bulk materials, amorphous solid dispersions as well as when included ...

A novel RP-HPLC method for the detection and quantification of roxithromycin in topical delivery studies

Aucamp, M.E.; Csongradi, C.; Gerber, M.; Du Plessis, J. (Govi-Verlag, 2015)

A novel HPLC method with UV detection for the identification and quantification of roxithromycin (ROX) during in vitro skin penetration studies has been developed and validated. The method proved to be simple and rapid ...

Novel S-adenosyl-L-methionine decarboxylase inhibitors as potent antiproliferative agents against intraerythrocytic Plasmodium falciparum parasites

Le Roux, Dina; Grobler, Anne; Burger, Pieter B.; Niemand, Jandeli; Urbán, Patricia (Elsevier, 2014)

S-adenosyl-L-methionine decarboxylase (AdoMetDC) in the polyamine biosynthesis pathway has been identified as a suitable drug target in Plasmodium falciparum parasites, which causes the most lethal form of malaria. ...

A Novel Schiff Base of 3-acetyl-4-hydroxy-6-methyl-(2H)pyran-2-one and 2,2'-(ethylenedioxy)diethylamine as Potential Corrosion Inhibitor for Mild Steel in Acidic Medium

Asegbeloying, Jonnie; Ejikeme, Paul; Olasunkanmi, Lukman Olawale; Adekunle, Abolanle; Ebenso, Eno Effiong (MDPI, 2015)

The corrosion inhibition activity of a newly synthesized Schiff base (SB) from 3-acetyl-4-hydroxy-6-methyl-(2H)-pyran-2-one and 2,2'-(ethylenedioxy)diethylamine was investigated on the corrosion of mild steel in 1 M HCl ...

Novel simulations for energy management of mine cooling systems

Maré, Philip (North-West University (South Africa) , Potchefstroom Campus, 2017)

The South African mining industry purchased 13.8% of the electricity supplied by Eskom in 2015. Deep-level mines are some of the largest electricity consumers in the mineral extraction industry. The electricity costs of ...

Novel software to reduce the risk of energy related illnesses

Rossouw, Jacobus Laurence (North-West University, 2006)

People often neglect their diets because of the effort required to ensure that they are maintaining a healthy diet. Most people do not know exactly what types of food and the amount they should eat without some guidance. ...

Novel solutions for compressed air demand management on deep-level mines

Zietsman, L.N. (North-West University (South Africa), 2020)

Mining makes a significant contribution to South Africa’s economy (7.3% of the gross domestic product) and provides direct employment to more than 450 000 people. The bulk of South Africa’s mineral wealth lies in deep-level ...

Novel sulfanylphthalimide analogues as highly potent inhibitors of monoamine oxidase B

Van der Walt, Mietha M.; Terre'Blanche, Gisella; Petzer, Anél; Petzer, Jacobus P. (Elsevier, 2012)

Monoamine oxidase (MAO) plays an essential role in the catabolism of neurotransmitter amines. The two isoforms of this enzyme, MAO-A and -B, are considered to be drug targets for the therapy of depression and neurodegenerative ...

Novel sulfanyl– and sulfinylcaffeine analogues as inhibitors of monoamine oxidase

Mentz, Wayne (North-West University, 2013)

Parkinson’s disease (PD) is a neurodegenerative disorder, which is progressive in nature and usually associated with the elderly. It is the second most common age-related neurodegenerative disorder after Alzheimer’s disease ...

A novel within a novel : a study of Doris Lessing's The golden notebook

Ribbens, Irene Rita (North-West University (South Africa), 1978)

"No abstract"

A novel, multi-faceted perception of lactate in neurology

Mason, Shayne (Frontiers Media, 2020)

Lactate has become one of the most re-evaluated metabolites in energy metabolism, particularly as a shuttle in neuroenergetics (Mason, 2017; Ferguson et al., 2018). In a comprehensive review in 2018, Brooks, one of the ...

Die novelles van S.A. Moroke : 'n literêre waardering

Nieuwenhuizen, Johan Coenraad (1981)

The aim of this study has been to produce a literary appreciation of five of S.A. Moroke's novelettes, with due reference to the problems surrounding the term 'novelette' and the recognition thereof as a sub-form of prose ...

Novice principals from Canada and South Africa and share their experiences

Mentz, Paulus Jacobus; Van der Walt, Johannes Lodewicus; Webber, Charles C.F. (Routledge, 2010)

De novo sequencing, assembly and annotation of the Agapornis roseicollis genome to identify variants for the development of genetic screening tests

Van der Zwan, Henriëtte (North-West University (South Africa). Potchefstroom Campus, 2019)

The genus Agapornis consists of nine small African parrots that are commonly called lovebirds. These birds are found in their natural habitat across Africa (eight species) and Madagascar (one species), but also house as ...