Browsing by Subject "Carotid intima-media thickness"
Now showing items 1-8 of 8
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Asymmetric dimethylarginine and l-homoarginine prospectively relate to carotid wall thickness in a South African cohort
(Springer, 2020)Background and aims The L-arginine derivatives asymmetric (ADMA) and symmetric dimethylarginine (SDMA), as well as L-homoarginine may have opposing effects in the pathogenesis of atherosclerosis. We aimed to investigate ... -
Attenuated IGF-1 predicts all-cause and cardiovascular mortality in a Black population: a five-year prospective study
(Sage Publications Ltd, 2016)Background: Inconsistent findings are reported on whether insulin-like growth factor-1 (IGF-1) is protective or harmful in predicting hypertension, carotid wall thickness and mortality. We determined the five-year ... -
Brain derived neurotrophic factor and structural vascular disease in black Africans : the SABPA study
(2014)Motivation - Brain-derived neurotrophic factor (BDNF) is a protein complex, synthesised and secreted mainly by the central nervous system and is involved in neuronal maintenance. Research suggests that BDNF is implicated ... -
Indices of calcium metabolism and their relationships with arterial structure and function in African women : the PURE study
(2013)Motivation - The burden of cardiovascular diseases (CVD) is increasing in developing countries worldwide, but even more so in sub-Saharan Africa. Due to rapid urbanisation, black populations experience lifestyle changes ... -
The link between vascular deterioration and branched chain amino acids in a population with high glycated haemoglobin: the SABPA study
(Springer Link, 2013)Globally the prevalence of non-communicable diseases, such as hypertension and type 2 diabetes, are escalating. Metabolomic studies indicated that circulating branched chain amino acids (BCAAs) are associated with insulin ... -
Monocyte chemoattractant protein-1 and large artery structure and function in young individuals : the African-PREDICT study
(North-West University (South Africa) , Potchefstroom Campus, 2015)Motivation - In sub-Saharan Africa, the burden of cardiovascular diseases (CVD) is increasing at an alarming rate. This may be due to the rapid urbanisation of traditional black populations, leading to lifestyle changes ... -
Nocturnal blood pressure, 3–methoxy–4–hydroxyphenylglycol and carotid intima–media thickness: the SABPA study
(Elsevier, 2013)Background: Research demonstrated a significant relationship between elevated nocturnal blood pressure and sym-pathetic hyperactivity. The study aimed to investigate possible associations between norepinephrine ... -
The role of endothelin-1 in cardiometabolic and vascular function in a bi-ethnic population : the SABPA study
(North-West University (South Africa) , Potchefstroom Campus, 2017)Motivation The black population in South Africa has a high prevalence of hypertension and atherosclerosis. Endothelin-1 (ET-1), a potent vasoconstrictor peptide, has been implicated as an important biomarker in the ...