Browsing by Subject "Isatin"
Now showing items 1-5 of 5
-
Anticorrosion performance of three newly synthesized isatin derivatives on carbon steel in hydrochloric acid pickling environment: electrochemical, surface and theoretical studies
(Elsevier, 2017)In this work, three new isatin derivatives (5-BEI, 5-HEI and 5-FEI) were synthesized and their inhibition effect on carbon steel in hydrochloric acid medium has been evaluated. The detailed study of 5-BEI is given using ... -
Inhibition of monoamine oxidase by C5-substituted phthalimide analogues
(Elsevier, 2011)Literature reports that isatin as well as C5- and C6-substituted isatin analogues are reversible inhibitors of human monoamine oxidase (MAO) A and B. In general, C5- and C6-substitution of isatin leads to enhanced binding ... -
Inhibition of monoamine oxidase by E-styrylisatin analogues
(Elsevier, 2009)Previous studies have shown that (E)-8-(3-chlorostyryl)caffeine (CSC) is a specific reversible inhibitor of human monoamine oxidase B (MAO-B) and does not bind to human MAO-A. Since the small molecule isatin is a natural ... -
Inhibition of monoamine oxidase by selected C5- and C6-substituted isatin analogues
(Elsevier, 2011)Previous studies have shown that (E)-5-styrylisatin and (E)-6-styrylisatin are reversible inhibitors of human monoamine oxidase (MAO) A and B. Both homologues are reported to exhibit selective binding to the MAO-B isoform ... -
Novel sulfanylphthalimide analogues as highly potent inhibitors of monoamine oxidase B
(Elsevier, 2012)Monoamine oxidase (MAO) plays an essential role in the catabolism of neurotransmitter amines. The two isoforms of this enzyme, MAO-A and -B, are considered to be drug targets for the therapy of depression and neurodegenerative ...