dc.contributor.author | Zatu, Mandlenkosi C. | |
dc.contributor.author | Van Rooyen, Johannes M. | |
dc.contributor.author | Du Toit, Loots | |
dc.contributor.author | Wentzel-Viljoen, Edelweiss | |
dc.contributor.author | Greeff, Minrie | |
dc.contributor.author | Schutte, Aletta E. | |
dc.date.accessioned | 2016-01-12T09:25:22Z | |
dc.date.available | 2016-01-12T09:25:22Z | |
dc.date.issued | 2014 | |
dc.identifier.citation | Zatu, M.C. et al. 2014. Self-reported alcohol intake is a better estimate of 5-year change in blood pressure than biochemical markers in low resource settings: the PURE study. Journal of hypertension, 32(4):749-755. [http://journals.lww.com/jhypertension/Abstract/2014/0400/Self_reported_alcohol_intake_is_a_better_estimate.10.aspx] | en_US |
dc.identifier.issn | 0041-4751 | |
dc.identifier.uri | http://hdl.handle.net/10394/15843 | |
dc.identifier.uri | http://dx.doi.org/10.1097/HJH.0000000000000093 | |
dc.description.abstract | Background: Despite criticism of self-reported alcohol intake, it is a valuable tool to screen for alcohol abuse as a risk factor for cardiovascular disease. We aimed to compare various self-reported estimates of alcohol use with γ-glutamyltransferase (GGT) and percentage carbohydrate deficient transferrin (%CDT) considering their relationship with blood pressure changes (%BP) over a 5-year period in black South Africans.
Method: We recruited 1994 participants and collected 5-year followed up data (N = 1246). Participants completed questionnaires on alcohol intake indicating their former and current alcohol use (‘yes’ response and ‘no’ if alcohol was never used). We assessed alcohol intake (in g) using a quantified food frequency questionnaire. We collected blood samples and measured GGT and %CDT. Brachial BP (bBP) was measured at baseline and follow-up and central BP (cBP) at follow-up only.
Results: Self-reported alcohol intake was significantly associated with the 5-year change in bBP before and after adjusting for confounders (%bSBP: R2 = 0.263, β = 0.06, P = 0.023; %bDBP: R2 = 0.326, β = 0.08 P = 0.005), as well as cSBP (R2 = 0.286, β = 0.09, P = 0.010) and central pulse pressure (R2 = 0.254, β = 0.06, P = 0.020). GGT and %CDT correlated well with self-reported alcohol intake (r = 0.44; P = 0.001; r = 0.34 P = 0.001), but did not associate significantly with %bBP or cBP at follow-up.
Conclusion: Self-reported alcohol use was strongly associated with a 5-year increase in BP in Africans with a low socio-economic status. This was not found for biochemical measures, GGT and %CDT. Self-reported alcohol intake could be an important measure to implement in primary healthcare settings in middle to low income countries, where honest reporting is expected. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Wolters Kluwer/Lippincott, Williams & Wilkins | en_US |
dc.subject | blood pressure | en_US |
dc.subject | cardiovascular disease | en_US |
dc.subject | g -glutamyltransferase | en_US |
dc.subject | hypertension | en_US |
dc.subject | low socio-economic status | en_US |
dc.subject | percentage carbohydrate deficient transferrin | en_US |
dc.subject | self- reported alcohol intake | en_US |
dc.title | Self-reported alcohol intake is a better estimate of 5-year change in blood pressure than biochemical markers in low resource settings: the PURE study | en_US |
dc.type | Article | en_US |
dc.contributor.researchID | 10059539 - Van Rooyen, Johannes Marthinus | |
dc.contributor.researchID | 10998497 - Wentzel-Viljoen, Edelweiss | |
dc.contributor.researchID | 10187308 - Greeff, Minrie | |
dc.contributor.researchID | 10922180 - Schutte, Aletta Elisabeth | |