Browsing Research Output by Author "5f3392ab-09d8-4a76-bf72-309a0b34fa80"
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Quinolone-isoniazid hybrids: synthesis and preliminary in vitro cytotoxicity and anti-tuberculosis evaluation
Beteck, Richard M.; Legoabe, Lesetja J.; Seldon, Ronnett; Jordaanc, Audrey; Warner, Digby F. (RSC, 2019)Herein, we propose novel quinolones incorporating an INH moiety as potential drug templates against TB. The quinolone-based compounds bearing an INH moiety attached via a hydrazide–hydrazone bond were synthesised and ...