Browsing Research Output by Author "df66f528-9086-4e6e-9872-e32b5c8497a0"
Now showing items 1-2 of 2
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Preliminary evaluation of artemisinin-cholesterol conjugates as potential drugs for the treatment of intractable forms of malaria and tuberculosis
Morake, Mokhitli; Wentzel, Johannes F.; Wong, Ho Ning; Smit, Frans J.; N'Da, David D.; Haynes, Richard K. (Wiley, 2018)To evaluate the feasibility of developing drugs that may be active against both malaria and tuberculosis (TB) by using in part putative cholesterol transporters in the causative pathogens and through enhancement of passive ... -
Synthesis and antimycobacterial activity of disubstituted benzyltriazoles
Smit, Frans J.; Aucamp, Janine; N'Da, David D.; Seldon, Ronnett; Jordaan, Audrey (Springer, 2019)The increasing prevalence of multidrug-resistant strains of Mycobacterium tuberculosis (Mtb), the pathogen of human tuberculosis (TB), serves as a strong incentive for the discovery and development of new agents for the ...