Browsing Research Output by Subject "Bioavailability"
Now showing items 1-9 of 9
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Beneficial pharmacokinetic drug interactions: a tool to improve the bioavailability of poorly permeable drugs
(MDPI, 2018)Simultaneous oral intake of herbs, supplements, foods and drugs with other drug(s) may result in pharmacokinetic or pharmacodynamic interactions with the latter. Although these interactions are often associated with unwanted ... -
Immobilization and phytotoxicity reduction of heavy metals in serpentine soil using biochar
(Springer, 2015)Purpose: Serpentine soils derived from ultramafic rocks release elevated concentrations of toxic heavy metals into the environment. Hence, crop plants cultivated in or adjacent to serpentine soil may experience reduced ... -
In vivo efficacy and bioavailability of lumefantrine: evaluating the application of Pheroid technology
(Elsevier, 2015)The oral absorption of compounds with low aqueous solubility, such as lumefantrine, is typically limited by the dissolution rate in the gastro-intestinal tract, resulting in erratic absorption and highly variable ... -
Influence of carbon nanotubes on the bioavailability of fluoranthene
(Wiley, 2015)Concurrent with the increase in the use of carbon nanotubes (CNTs) in society is the rise of their introduction into the environment. Carbon nanotubes cause adverse effects themselves, and they have the potential to adsorb ... -
Metal retention potential of sediment and water quality in the Mooi River, South Africa
(Taylor & Francis, 2017)The potential metal retention by sediments along the Mooi River and connected streams in the vicin - ity of Potchefstroom, South Africa, was evaluated using the four-stage sequential extraction proce - dure. ... -
Modeling nanoparticle delivery of TB drugs to granulomas
(Elsevier, 2016)Tuberculosis, which typically presents as a pulmonary disease, has a complex pathology. The primary site of infection, the Ghon focus, recruits immune cells and a granuloma forms. At earlier stages the granuloma is still ... -
Phytochemical uptake following human consumption of Montmorency tart cherry (L. Prunus cerasus) and influence of phenolic acids on vascular smooth muscle cells in vitro
(Springer, 2016)Purpose To investigate the phytochemical uptake following human consumption of Montmorency tart cherry (L. Prunus cerasus) and influence of selected phenolic acids on vascular smooth muscle cells in vitro. Methods In a ... -
The plasma bioavailability of nitrate and betanin from Beta vulgaris rubra in humans
(Springer, 2017)Purpose To evaluate the plasma bioavailability of betanin and nitric oxide (NOx) after consuming beetroot juice (BTJ) and whole beetroot (BF). BTJ and BF were also analysed for antioxidant capacity, polyphenol content ... -
The role of functional excipients in solid oral dosage forms to overcome poor drug dissolution and bioavailability
(MDPI, 2020)Many active pharmaceutical ingredients (APIs) exhibit poor solubility and low dissolution rates in aqueous environments such as the luminal fluids of the gastrointestinal tract. The oral bioavailability of these compounds ...