Browsing Research Output by Subject "Bluetongue virus"
Now showing items 1-10 of 10
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Application of Bluetongue Disabled Infectious Single Animal (DISA) vaccine for different serotypes by VP2 exchange or incorporation ofchimeric VP2
(Elsevier, 2015)Bluetongue is a disease of ruminants caused by the bluetongue virus (BTV). Bluetongue outbreaks can be controlled by vaccination, however, currently available vaccines have several drawbacks. Further, there are at least ... -
Bluetongue Disabled Infectious Single Animal (DISA) vaccine: studies on the optimal route and dose in sheep
(Elsevier, 2017)Bluetongue (BT) is a disease of ruminants caused by bluetongue virus (BTV) transmitted by biting midges of the Culicoides genus. Outbreaks have been controlled successfully by vaccination, however, currently available BT ... -
European bluetongue serotype 8: disease threat assessment for U.S. sheep
(Mary Ann Liebert Inc, 2016)Bluetongue virus (BTV) is an orbivirus transmitted by biting midges (Culicoides spp.) that can result in moderate to high morbidity and mortality primarily in sheep and white-tailed deer. Although only 5 serotypes of BTV ... -
Experimental infection of small ruminants with bluetongue virus expressing Toggenburg Orbivirus proteins
(Elsevier, 2016)Bluetongue virus (BTV) is the prototype orbivirus (Reoviridae family, genus Orbivirus) consisting of more than 24 recognized serotypes or neutralization groups. Recently, new BTV serotypes in goats have been found; serotype ... -
Non-structural protein NS3/NS3a is required for propagation of bluetongue virus in Culicoides sonorensis
(BioMed Central, 2015)Background: Bluetongue virus (BTV) causes non-contagious haemorrhagic disease in ruminants and is transmitted by Culicoides spp. biting midges. BTV encodes four non-structural proteins of which NS3/NS3a is functional in ... -
Replication-deficient particles: new insights into the next generation of bluetongue virus vaccines
(American Society for Microbiology, 2017)Bluetongue virus (BTV) is endemic in many parts of the world, often causing severe hemorrhagic disease in livestock. To date, at least 27 different sero- types have been recognized. Vaccination against all serotypes is ... -
Requirements and comparative analysis of reverse genetics for bluetongue virus (BTV) and African horse sickness virus (AHSV)
(BioMed Central, 2016)Background Bluetongue virus (BTV) and African horse sickness virus (AHSV) are distinct arthropod borne virus species in the genus Orbivirus (Reoviridae family), causing the notifiable diseases Bluetongue and African horse ... -
A review of knowledge gaps and tools for orbivirus research
(Mary Ann Liebert, Inc, 2015)Although recognized as causing emerging and re-emerging disease outbreaks worldwide since the late 1800s, there has been growing interest in the United States and Europe in recent years in orbiviruses, their insect vectors, ... -
Vector competence is strongly affected by a small deletion or point mutations in bluetongue virus
(BMC, 2019)Background Transmission of vector-borne virus by insects is a complex mechanism consisting of many different processes; viremia in the host, uptake, infection and dissemination in the vector, and delivery of virus during ... -
Viral replication kinetics and in vitro cytopathogenicity of parental and reassortant strains of bluetongue virus serotype 1, 6 and 8
(Elsevier, 2014)Bluetongue virus (BTV), a segmented dsRNA virus, is the causative agent of bluetongue (BT), an economically important viral haemorrhagic disease of ruminants. Bluetongue virus can exchange its genome segments in mammalian ...