Browsing Research Output by Subject "GCxGC-TOFMS"
Now showing items 1-8 of 8
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Assessment of polar organic aerosols at a regional background site in southern Africa
(Springer, 2019)A recent paper reported GCxGC-TOFMS analysis used for the first time in southern Africa to tentatively characterise and semi-quantify ~1000 organic compounds in aerosols at Welgegund – a regional background atmospheric ... -
Characterising particulate organic nitrogen at a savannah-grassland region in South Africa
(MDPI, 2019)Although atmospheric organic N compounds are considered to be important, especially in new particle formation and their contribution to brown carbon, these species are not that well understood. This can be partially ... -
A comparison of four sputum pre-extraction preparation methods for identifying and characterising Mycobacterium tuberculosis using GCxGC-TOFMS metabolomics
(Elsevier, 2012)In many pulmonary diseases, sputum is a valuable sample material for use in disease characterisation and diagnostics. However, due to its high viscosity and uneven consistency (lumpiness), it is difficult to obtain ... -
A metabolomics investigation of the function of the ESX-1 gene cluster in mycobacteria
(Elsevier, 2016)The ESX-1 gene cluster, encoding the Type-VII secretion (T7S) system and its virulence associated proteins, ESAT-6 and CFP-10, is thought to be responsible for the transport of extracellular proteins across the hydrophobic ... -
Mycobacterium tuberculosis curli pili (MTP) is associated with significant host metabolic pathways in an A549 epithelial cell infection model and contributes to the pathogenicity of Mycobacterium tuberculosis
(Springer, 2020)Introduction A clear understanding of the metabolome of Mycobacterium tuberculosis and its target host cell during infection is fundamental for the development of novel diagnostic tools, effective drugs and vaccines ... -
Mycobacterium tuberculosis curli pili (MTP) is associated with significant host metabolic pathways in an A549 epithelial cell infection model and contributes to the pathogenicity of Mycobacterium tuberculosis
(Springer, 2020)Introduction A clear understanding of the metabolome of Mycobacterium tuberculosis and its target host cell during infection is fundamental for the development of novel diagnostic tools, effective drugs and vaccines ... -
Size-resolved characterisation of organic compounds in atmospheric aerosols collected at Welgegund, South Africa
(Springer, 2015)The organic fraction of atmospheric aerosols is 20 to 90 % of which only a small percentage has been chemically characterised. Two-dimensional gas chromatography with a time-of-flight mass spectrometer (GCxGC-TOFMS) is a ... -
Supercritical carbon dioxide extracted oil from Jatropha curcas: directive for the biodiesel industry?
(Elsevier, 2011)Jatropha curcas oil was extracted from seed by supercritical carbon dioxide (sc-CO2) and converted to a biodiesel in support of a world-wide search for a sustainable energy source produced by clean technology to replace ...