Now showing items 1-2 of 2

    • Metabolomics of mitochondrial disease 

      Esterhuizen, Karien; Van der Westhuizen, Francois H.; Louw, Roan (Elsevier, 2017)
      Mitochondrial disease (MD) diagnostics and disease progression investigations have traditionally relied very little on metabolic data, due to a lack of biomarker sensitivity and specificity. The recent drive to find novel, ...
    • Untargeted urine metabolomics reveals a biosignature for muscle respiratory chain deficiencies 

      Venter, Leonie; Lindeque, Zander; Jansen van Rensburg, Peet; Van der Westhuizen, Francois; Louw, Roan (Springer, 2015)
      Mitochondrial diseases are a heterogeneous group of disorders characterised by impaired mitochondrial oxidative phosphorylation system. Most often for mitochondrial disease, where no metabolic diagnostic biomarkers exist, ...