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Browsing Research Output by Subject "Cardiomyocyte"
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Considerations for an in vitro, cell-based testing platform for detection of adverse drug-induced inotropic effects in early drug development. Part 1: General considerations for development of novel testing platforms (Frontiers Media, 2019)Drug-induced effects on cardiac contractility can be assessed through the measurement of the maximal rate of pressure increase in the left ventricle (LVdP/dtmax) in conscious animals, and such studies are often conducted ...