Browsing Research Output by Subject "Clofazimine"
Now showing items 1-3 of 3
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Development of a self-emulsifying drug delivery system for optimized topical delivery of clofazimine
(MDPI, 2020)A quality-by-design and characterization approach was followed to ensure development of self-emulsifying drug delivery systems (SEDDSs) destined for topical delivery of the highly lipophilic clofazimine. Solubility and ... -
Formulation of natural oil nano-emulsions for the topical delivery of clofazimine, artemisone and decoquinate
(Springer, 2018)Purpose The aim of this study was to formulate nano-emulsions comprising natural oils and the active pharmaceutical ingredients (APIs) clofazimine (CLF), artemisone (ATM) and decoquinate (DQ) in order to determine ... -
Topical delivery of artemisone, clofazimine and decoquinate encapsulated in vesicles and their in vitro efficacy against Mycobacterium tuberculosis
(Springer, 2019)Vesicles are widely investigated as carrier systems for active pharmaceutical ingredients (APIs). For topical delivery, they are especially effective since they create a “depot-effect” thereby concentrating the APIs in the ...