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The link between vascular deterioration and branched chain amino acids in a population with high glycated haemoglobin: the SABPA study
(Springer Link, 2013)
Globally the prevalence of non-communicable diseases, such as hypertension and type 2 diabetes, are escalating. Metabolomic studies indicated that circulating branched chain amino acids (BCAAs) are associated with insulin ...
Double product and end-organ damage in African and Caucasian men: the SABPA study
(ELSEVIER, 2013)
Background: Increasing urbanisation in sub-Saharan African countries is causing a rapid increase in cardiovascular
disease. Evidence suggests that Africans have higher blood pressures and a higher prevalence of
hyperte ...
Cardiometabolic markers to identify cardiovascular disease risk in HIV-infected black South Africans
(2014)
Background.
The prevalence of HIV is the highest in sub-Saharan Africa; South Africa (SA) is one of the most affected countries with the
highest number of adults living with HIV infection in the world. Besides ...
Recent advances in understanding hypertension development in sub-Saharan Africa
(Nature, 2017)
Consistent reports indicate that hypertension is a particularly common finding in black populations. Hypertension occurs at
younger ages and is often more severe in terms of blood pressure levels and organ damage than in ...
Lack of association of glycated haemoglobin with blood pressure and subclinical atherosclerosis in black South Africans: a five-year prospective study
(MedPharm Publications (Medical and Pharmaceutical Publications), 2013)
Objectives: Hypertension and diabetes are common in rapidly urbanising sub-Saharan African communities.
However, lack of longitudinal data in these regions prevents adequate analysis of the link between measures of
glycaemia ...
A comparison of the association between glomerular filtration and L-arginine status in HIV-infected and uninfected African men: the SAfrEIC study
(Nature Publishing Group, 2013)
Hypertension, a major risk factor for cardiovascular disease worldwide, is increasing significantly in urbanised South Africans.
Impaired glomerular filtration is a potential contributor to hypertension. Although HIV ...
8-Oxo-7,8-dihydro-2’-deoxyguanosine, reactive oxygen species and ambulatory blood pressure in African and Caucasian men: the SABPA study
(Taylor & Francis, 2014)
Various studies indicate a relationship between increased oxidative stress and hypertension, resulting in increased DNA damage and consequent excretion of 8-oxo-7,8-dihydro-2’-deoxyguanosine (8-oxodG). The aim of this study ...
Deriving an optimal threshold of waist circumference for detecting cardiometabolic risk in sub-Saharan Africa
(Nature, 2018)
BACKGROUND: Waist circumference (WC) thresholds derived from western populations continue to be used in sub-Saharan Africa
(SSA) despite increasing evidence of ethnic variation in the association between adiposity and ...
Relationship of coagulation and fibrinolytic variables with arterial structure and function in Africans
(Elsevier, 2014)
Introduction
Although both coagulation and fibrinolysis are associated with cardiovascular disease (CVD) the underlying nature and pathways of many of these associations are still unclear. Our aim was to determine which ...
Endothelial activation and cardiometabolic profiles of treated and never–treated HIV infected Africans
(Elsevier, 2015)
The role the human immunodeficiency virus (HIV) and antiretroviral treatment on endothelial activation, and the subsequent relationship with cardiovascular disease, is not well understood. We investigated endothelial ...