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A metabolomics approach exploring the function of the ESX-3 type VII secretion system of M. smegmatis
The genome of Mycobacterium, including Mycobacterium tuberculosis, contains five copies of a cluster of genes encoding a novel type VII secretion system, named the ESX gene cluster region. This ESX-3 gene cluster is ...
A metabolomics investigation of the function of the ESX-1 gene cluster in mycobacteria
The ESX-1 gene cluster, encoding the Type-VII secretion (T7S) system and its virulence associated proteins, ESAT-6 and CFP-10, is thought to be responsible for the transport of extracellular proteins across the hydrophobic ...