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Revival of unsuccessful chemotherapeutics for highly glycolytic cancers?
(Elsevier, 2011)
Around 90% of cancer deaths can be ascribed to metastases , usually highly glycolytic. Rodent models are used when developing drugs to attack these cancers
High-glycolytic cancers and their interplay with the body's glucose demand and supply cycle
(Elsevier, 2011)
Many difficult-to-treat solid cancer tumours and metastases have high-glucose uptake, usually under hypoxic conditions. Hypoxic tumours suppress the immune system and are insensitive to traditional chemoradiotherapies. The ...
Prelimanary application of a new Bolus Insulin model for Type 1 Diabetes
(Mary Ann Liebert, 2011)
Previous work derived a theoretically rigorous bolus insulin model. It was shown that the new model predicts insulin response of subjects without diabetes substantially better than the carbohydrate counting method (CHOcm). ...