Now showing items 1-5 of 5
Concurrent class analysis identifies discriminatory variables from metabolomics data on isovaleric acidemia
Metabolomics data are typically complex and high dimensional. Multivariate dimension-reducing techniques have thus been developed for analysing metabolomics data to disclose underlying relationships, with principal component ...
Metabolomics of urinary organic acids in respiratory chain deficiencies in children
Metabolomic analysis of the urinary organic acids from 39 selected children with defined respiratory chain deficiencies (RCDs) was performed using untargeted gas chromatography–mass spectrometry, revealing the presence ...
A comparison of two extraction methods for differentiating and characterising various Mycobacterium species and Pseudomonas aeruginosa using GC-MS metabolomics
(Academic Journals, 2012)
We investigated the capacity of a metabolomics research approach to characterise and differentiate between various infectious Mycobacterium species and Pseudomonas aeruginosa, and compared two extraction procedures; 1) ...
A comparison of four sputum pre-extraction preparation methods for identifying and characterising Mycobacterium tuberculosis using GCxGC-TOFMS metabolomics
In many pulmonary diseases, sputum is a valuable sample material for use in disease characterisation and diagnostics. However, due to its high viscosity and uneven consistency (lumpiness), it is difficult to obtain ...
A metabolomics approach to characterise and identify various Mycobacterium species
We investigated the potential use of gas chromatography mass spectrometry (GC–MS), in combination with multivariate statistical data processing, to build a model for the classification of various tuberculosis (TB) causing, ...