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The cross-tissue metabolic response of abalone (Haliotis midae) to functional hypoxia
(The Company of Biologists, 2018)
Functional hypoxia is a stress condition caused by the abalone itself as
a result of increased muscle activity, which generally necessitates the
employment of anaerobic metabolism if the activity is sustained for
prolonged ...
Uncovering the metabolic response of abalone (Haliotis midae) to environmental hypoxia through metabolomics
(Springer, 2018)
Introduction
Oxygen is essential for metabolic processes and in the absence thereof alternative metabolic pathways are required for energy production, as seen in marine invertebrates like abalone. Even though hypoxia has ...
Miniaturized 1H-NMR method for analyzing limited-quantity samples applied to a mouse model of Leigh disease
(Springer, 2018)
Introduction
The analysis of limited-quantity samples remains a challenge associated with mouse models, especially for multi-platform metabolomics studies. Although inherently insensitive, the highly specific characteristics ...
Metabolomics reveals the depletion of intracellular metabolites in HepG2 cells after treatment with gold nanoparticles
(Taylor & Francis, 2018)
Studies on the safety of gold nanoparticles (GNPs) are plentiful due to their successful application in drug delivery and treatment of diseases in trials. Cytotoxicity caused by GNPs has been studied on the physiological ...
GC-MS-based urinary organic acid profiling reveals multiple dysregulated metabolic pathways following experimental acute alcohol consumption
(Nature, 2018)
Metabolomics studies of diseases associated with chronic alcohol consumption provide compelling evidence of several perturbed metabolic pathways. Moreover, the holistic approach of such studies gives insights into the ...
Abalone growth and associated aspects: now from a metabolic perspective
(Wiley, 2018)
Worldwide, there are approximately 100 Haliotis species, more commonly known as abalone or ‘Paua’ in New Zealand, ‘Venus's‐ears’ in Greece, ‘Awabi’ in Japan, ‘Perlemoen’ in South Africa and ‘Ormers’ in Europe. Regardless ...
The altered human serum metabolome induced by a marathon
(Springer, 2018)
Introduction
Endurance races have been associated with a substantial amount of adverse effects which could lead to chronic disease and long-term performance impairment. However, little is known about the holistic metabolic ...
Novel insights into the pharmacometabonomics of first-line tuberculosis drugs relating to metabolism, mechanism of action and drug-resistance
(Taylor & Francis, 2018)
The World Health Organization recommends the directly observed therapy short-course (DOTS) regimen, a combination of four first-line antibiotics (isoniazid, rifampicin, pyrazinamide and ethambutol), for the treatment of ...
Urinary metabolites and their link with premature arterial stiffness in black boys: the ASOS study
(Karger, 2018)
Background and Aims: Black boys (6–8 years of age) were shown to have higher pulse wave
velocity with potential early vascular compromise. We aimed to compare predefined urinary
metabolites in black and white boys to ...
Miniaturized 1H-NMR method for analyzing limited-quantity samples applied to a mouse model of Leigh disease
(Springer, 2018)
Introduction
The analysis of limited-quantity samples remains a challenge associated with mouse models, especially for multi-platform metabolomics studies. Although inherently insensitive, the highly specific characteristics ...