• Login
    Search 
    •   NWU-IR Home
    • Research Output
    • Search
    •   NWU-IR Home
    • Research Output
    • Search
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Search

    Show Advanced FiltersHide Advanced Filters

    Filters

    Use filters to refine the search results.

    Now showing items 1-10 of 14

    • Sort Options:
    • Relevance
    • Title Asc
    • Title Desc
    • Issue Date Asc
    • Issue Date Desc
    • Results Per Page:
    • 5
    • 10
    • 20
    • 40
    • 60
    • 80
    • 100
    Thumbnail

    Novel insights into the pharmacometabonomics of first-line tuberculosis drugs relating to metabolism, mechanism of action and drug-resistance 

    Du Preez, Ilse; Loots, Du Toit (Taylor & Francis, 2018)
    The World Health Organization recommends the directly observed therapy short-course (DOTS) regimen, a combination of four first-line antibiotics (isoniazid, rifampicin, pyrazinamide and ethambutol), for the treatment of ...
    Thumbnail

    The altered human serum metabolome induced by a marathon 

    Stander, Zinandré; Luies, Laneke; Mienie, Lodewyk J.; Howatson, Glyn; Loots, Du Toit (Springer, 2018)
    Introduction Endurance races have been associated with a substantial amount of adverse effects which could lead to chronic disease and long-term performance impairment. However, little is known about the holistic metabolic ...
    Thumbnail

    Abalone growth and associated aspects: now from a metabolic perspective 

    Venter, Leonie; Loots, Du Toit; Jansen van Rensburg, Peet; Lindeque, Jeremie Zander; Vosloo, Andre (Wiley, 2018)
    Worldwide, there are approximately 100 Haliotis species, more commonly known as abalone or ‘Paua’ in New Zealand, ‘Venus's‐ears’ in Greece, ‘Awabi’ in Japan, ‘Perlemoen’ in South Africa and ‘Ormers’ in Europe. Regardless ...
    Thumbnail

    Metabolomics reveals the depletion of intracellular metabolites in HepG2 cells after treatment with gold nanoparticles 

    Lindeque, Jeremie Zander; Matthyser, Alnari; Mason, Shayne; Louw, Roan; Taute, Cornelius Johannes Francois (Taylor & Francis, 2018)
    Studies on the safety of gold nanoparticles (GNPs) are plentiful due to their successful application in drug delivery and treatment of diseases in trials. Cytotoxicity caused by GNPs has been studied on the physiological ...
    Thumbnail

    The cross-tissue metabolic response of abalone (Haliotis midae) to functional hypoxia 

    Venter, Leonie; Loots, Du Toit; Mienie, Lodewyk J.; Jansen van Rensburg, Peet J.; Mason, Shayne; Lindeque, Jeremie Z. (The Company of Biologists, 2018)
    Functional hypoxia is a stress condition caused by the abalone itself as a result of increased muscle activity, which generally necessitates the employment of anaerobic metabolism if the activity is sustained for prolonged ...
    Thumbnail

    Uncovering the metabolic response of abalone (Haliotis midae) to environmental hypoxia through metabolomics 

    Venter, Leonie; Loots, Du Toit; Mienie, Lodewyk Japie; Jansen van Rensburg, Peet J.; Mason, Shayne; Lindeque, Jeremie Zander (Springer, 2018)
    Introduction Oxygen is essential for metabolic processes and in the absence thereof alternative metabolic pathways are required for energy production, as seen in marine invertebrates like abalone. Even though hypoxia has ...
    Thumbnail

    Miniaturized 1H-NMR method for analyzing limited-quantity samples applied to a mouse model of Leigh disease 

    Mason, Shayne; Terburgh, Karin; Louw, Roan (Springer, 2018)
    Introduction The analysis of limited-quantity samples remains a challenge associated with mouse models, especially for multi-platform metabolomics studies. Although inherently insensitive, the highly specific characteristics ...
    Thumbnail

    Urinary metabolites and their link with premature arterial stiffness in black boys: the ASOS study 

    Erasmus, Dalene; Mels, Carina M.C.; Louw, Roan; Lindeque, J. Zander; Kruger, Ruan (Karger, 2018)
    Background and Aims: Black boys (6–8 years of age) were shown to have higher pulse wave velocity with potential early vascular compromise. We aimed to compare predefined urinary metabolites in black and white boys to ...
    Thumbnail

    Metabolomic response to coffee consumption: application to a three‐stage clinical trial 

    Cornelis, M.C.; Westerhuis, J.A.; Erlund, I.; Michelotti, G.A.; Herder, C. (Wiley, 2018)
    Background Coffee is widely consumed and contains many bioactive compounds, any of which may impact pathways related to disease development. Objective To identify individual metabolite changes in response to ...
    Thumbnail

    Elucidating the antimicrobial mechanisms of colistin sulfate on Mycobacterium tuberculosis using metabolomics 

    Koen, Nadia; Loots, Du Toit; Van Breda, Shane Vontelin (Elsevier, 2018)
    Considering the disadvantageous of first line anti-tuberculosis (TB) drugs, including poor patient adherence, drug side effects, the long treatment duration and rapidly increasing microbe resistance, alternative treatment ...
    • 1
    • 2

    Copyright © North-West University
    Contact Us | Send Feedback
    Theme by 
    @mire NV
     

     

    Browse

    All of NWU-IR Communities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CommunityBy Issue DateAuthorsTitlesSubjects

    My Account

    LoginRegister

    Discover

    AuthorLoots, Du Toit (7)Mason, Shayne (6)Lindeque, Jeremie Zander (4)Louw, Roan (4)Venter, Leonie (4)Jansen van Rensburg, Peet J. (3)Mienie, Lodewyk J. (3)Koen, Nadia (2)Terburgh, Karin (2)Van Breda, Shane Vontelin (2)... View MoreSubject
    Metabolomics (14)
    Metabolism (4)Abalone (3)Aquaculture (3)Antibiotics (2)Growth (2)Miniaturized (2)Mouse model studies (2)Mycobacterium tuberculosis (2)Ndufs4 KO mice, Leigh disease (2)... View MoreDate Issued
    2018 (14)

    Copyright © North-West University
    Contact Us | Send Feedback
    Theme by 
    @mire NV