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A urinary biosignature for mitochondrial myopathy, encephalopathy, lactic acidosis and stroke like episodes (MELAS)
We used a comprehensive metabolomics approach to study the altered urinary metabolome of two mitochondrial myopathy, encephalopathy lactic acidosis and stroke like episodes (MELAS) cohorts carrying the m.3243A>G mutation. The ...
Abalone growth and associated aspects: now from a metabolic perspective
Worldwide, there are approximately 100 Haliotis species, more commonly known as abalone or ‘Paua’ in New Zealand, ‘Venus's‐ears’ in Greece, ‘Awabi’ in Japan, ‘Perlemoen’ in South Africa and ‘Ormers’ in Europe. Regardless ...
The cross-tissue metabolic response of abalone (Haliotis midae) to functional hypoxia
(The Company of Biologists, 2018)
Functional hypoxia is a stress condition caused by the abalone itself as a result of increased muscle activity, which generally necessitates the employment of anaerobic metabolism if the activity is sustained for prolonged ...
Uncovering the metabolic response of abalone (Haliotis midae) to environmental hypoxia through metabolomics
Introduction Oxygen is essential for metabolic processes and in the absence thereof alternative metabolic pathways are required for energy production, as seen in marine invertebrates like abalone. Even though hypoxia has ...
Characterising the metabolic differences related to growth variation in farmed Haliotis midae
The South African abalone farming industry is entirely based on Haliotis midae, which has been commercially cultured with great success the last 20 years. Even though abalone are cultivated under identical farming conditions, ...
Metabolomics of mitochondrial disease
Mitochondrial disease (MD) diagnostics and disease progression investigations have traditionally relied very little on metabolic data, due to a lack of biomarker sensitivity and specificity. The recent drive to find novel, ...