Now showing items 1-2 of 2
Inhibition of monoamine oxidase by indole-5,6-dicarbonitrile derivatives
Recent studies have found that phthalonitrile derivatives are remarkably potent inhibitors of human monoamine oxidase (MAO) A and B. In an attempt to further determine the structure-activity relationships (SARs) for MAO ...
The synthesis and evaluation of C7-substituted α-tetralone derivatives as inhibitors of monoamine oxidase
Based on a previous report that α-tetralone (3,4-dihydro-2H-naphthalen-1-one) is a promising scaffold for the design of highly potent inhibitors of the enzyme, monoamine oxidase, the present study investigates the monoamine ...