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The cross-tissue metabolic response of abalone (Haliotis midae) to functional hypoxia
(The Company of Biologists, 2018)
Functional hypoxia is a stress condition caused by the abalone itself as
a result of increased muscle activity, which generally necessitates the
employment of anaerobic metabolism if the activity is sustained for
prolonged ...
GC-MS-based urinary organic acid profiling reveals multiple dysregulated metabolic pathways following experimental acute alcohol consumption
(Nature, 2018)
Metabolomics studies of diseases associated with chronic alcohol consumption provide compelling evidence of several perturbed metabolic pathways. Moreover, the holistic approach of such studies gives insights into the ...
TB or not TB? Improving the understanding and diagnosis of tuberculosis through metabolomics
(Future Medicine, 2016)
“
...metabolomics has resulted in an exponential increase in the
number of newly identified tuberculosis biomarkers, which has not
only shed light on previously unknown disease mechanisms, but could
potentially ...
Urinary metabolites and their link with premature arterial stiffness in black boys: the ASOS study
(Karger, 2018)
Background and Aims: Black boys (6–8 years of age) were shown to have higher pulse wave
velocity with potential early vascular compromise. We aimed to compare predefined urinary
metabolites in black and white boys to ...
Central systolic pressure and a nonessential amino acid metabolomics profile: the African prospective study on the early detection and identification of cardiovascular disease and hypertension
(Wolters Kluwer, 2019)
Objectives: Early-life exposures to cardiovascular risk factors may manifest as early vascular ageing, a phenomenon to which black populations are more prone. The metabolome provides insight into the current state and ...
Metabolomics biomarkers for tuberculosis diagnostics: current status and future objectives
(Future Medicine, 2017)
Numerous studies have contributed to our current understanding of the complex biology of pulmonary tuberculosis and subsequently provided solutions to its control or eradication. Metabolomics, a newcomer to the Omics ...
Metabolomics variable selection and classification in the presence of observations below the detection limit using an extension of ERp
(BioMed Central, 2017)
Background
ERp is a variable selection and classification method for metabolomics data. ERp uses minimized classification error rates, based on data from a control and experimental group, to test the null hypothesis of ...
A diagnostic biomarker profile for fibromyalgia syndrome based on an NMR metabolomics study of selected patients and controls
(BioMed Central, 2017)
Background:
Fibromyalgia syndrome (FMS) is a chronic pain syndrome. A plausible pathogenesis of the disease is
uncertain and the pursuit of measurable biomarkers for objective identification of affected individuals is a ...
A comparison of two extraction methods for differentiating and characterising various Mycobacterium species and Pseudomonas aeruginosa using GC-MS metabolomics
(Academic Journals, 2012)
We investigated the capacity of a metabolomics research approach to characterise and differentiate between various infectious Mycobacterium species and Pseudomonas aeruginosa, and compared two extraction procedures; 1) ...
Fetal metabolic stress disrupts immune homeostasis and induces proinflammatory responses in human immunodeficiency virus type 1- and combination antiretroviral therapy-exposed infants
(Oxford Univ Press, 2017)
Increased morbidity and fetal growth restriction are reported in uninfected children born to human immunodeficiency virus type 1 (HIV-1)–infected women treated with antiretroviral (ARV) therapy. Viruses and/or pharmacological ...