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The African prospective study on the early detection and identification of cardiovascular disease and hypertension (African-PREDICT): design, recruitment and initial examination
(Sage, 2019)
Background: Globally hypertension is stabilising, but in sub-Saharan Africa the incidence of hypertension remains on an
increase. Although this might be attributed to poor healthcare and ineffective antihypertensive ...
Leptin and the retinal microvasculature in young black and white adults: the African-PREDICT study
(Elsevier, 2020)
Background
Leptin is a vasoactive peptide that has been linked to diseases associated with macrovascular deterioration. What is still uncertain is its involvement in the microvasculature. Since microvascular changes are ...
Retinal vessel caliber and caliber responses in true normotensive black and white adults: the African-PREDICT study
(Elsevier, 2020)
Purpose
Globally, a detrimental shift in cardiovascular disease risk factors and a higher mortality level are reported in some black populations. The retinal microvasculature provides early insight into the pathogenesis ...
Von Willebrand factor, its cleaving protease (ADAMTS13), and inflammation in young adults: the African-PREDICT study
(Elsevier, 2020)
Background
The role of inflammation in the early development of vascular dysfunction remains complex. Interleukin-6 (IL-6) and C-reactive protein (CRP) can cause an acute imbalance in the von Willebrand factor (vWF)-ADAMTS13 ...
The Exercise, Arterial Modulation and Nutrition in Youth South Africa Study (ExAMIN Youth SA)
(Frontiers Media, 2020)
Background: The impact of a sedentary and unhealthy lifestyle on cardiovascular
health is well-documented, however the current obesity and hypertension trends among
children is concerning. The ExAMIN Youth SA study aims ...
The association of measures of the micro- and macro-vasculature with selenium and GPx activity in a young bi-ethnic population: the African-PREDICT study
(Taylor & Francis, 2019)
Objective: Selenium plays an important physiological role as component for antioxidant selenoproteins such as glutathione peroxidase (GPx). Since oxidative stress contributes to hypertension development, it is likely that ...
Heart rate variability, the dynamic nature of the retinal microvasculature and cardiac stress: providing insight into the brain-retina-heart link: the SABPA study + Correction
(Nature, 2020)
Background and aims
Decreased heart-rate-variability (HRV) indicates increased sympathetic nervous system (SNS) activity and modulation with a shift in the sympatho-vagal balance towards SNS predominance. Increased SNS ...
Retinal vasculature reactivity during flicker light provocation, cardiac stress and stroke risk in Africans: the SABPA study
(Springer, 2019)
Structural and functional similarities exist between the retinal, cerebral and, as previously suggested, the coronary microvasculature. Retinal microvascular structure and functionality (in response to flicker-light-indu ...
Correction to: Heart rate variability, the dynamic nature of the retinal microvasculature and cardiac stress: providing insight into the brain–retina–heart link: the SABPA study
(Springer, 2020)
Correction to: Eye
https://doi.org/10.1038/s41433-019-0515-y
Since the online publication of this article, the authors have noticed that the conclusion to the abstract contains an error. The correct abstract conclusion ...
Sex hormones associated with subclinical kidney damage and atherosclerosis in South African men: the SABPA study
(Kluwer, 2012)
Background: Hypertension and increased blood glucose are associated with subclinical kidney damage, atherosclerosis and with low testosterone values. Low testosterone in men is often accompanied by increased levels of ...