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Now showing items 21-26 of 26
A comparison of four sputum pre-extraction preparation methods for identifying and characterising Mycobacterium tuberculosis using GCxGC-TOFMS metabolomics
(Elsevier, 2012)
In many pulmonary diseases, sputum is a valuable sample material for use in disease characterisation and diagnostics. However, due to its high viscosity and uneven consistency (lumpiness), it is difficult to obtain ...
Urinary metabolite markers characterizing tuberculosis treatment failure
(Springer, 2017)
Background
Considering that approximately 15% of the nine million new tuberculosis (TB) cases reported per annum are not treated successfully, new, distinctive and specific biomarkers are needed to better characterize the ...
The role of metabolomics in tuberculosis treatment research
(Future Medicine, 2017)
Despite the fact that tuberculosis (TB) is a curable disease, it still results in approximately 1.8 million deaths annually. Various inadequacies in the current TB treatment strategies are major contributors to this high ...
Characterising the metabolic differences related to growth variation in farmed Haliotis midae
(Elsevier, 2018)
The South African abalone farming industry is entirely based on Haliotis midae, which has been commercially cultured with great success the last 20 years. Even though abalone are cultivated under identical farming conditions, ...
Elucidating the antimicrobial mechanisms of colistin sulfate on Mycobacterium tuberculosis using metabolomics
(Elsevier, 2018)
Considering the disadvantageous of first line anti-tuberculosis (TB) drugs, including poor patient adherence, drug side effects, the long treatment duration and rapidly increasing microbe resistance, alternative treatment ...
Tween 80 induces a carbon flux rerouting in Mycobacterium tuberculosis
(Elsevier, 2020)
As a means to increase the growth rate and reduce aggregation, Tween 80 is routinely added to growth media during mycobacterial culturing. This detergent has, however, been associated with causing alterations to the ...