Faculty of Health Sciences
Recent Submissions
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The performance of wearable sensors in the detection of SARS-CoV-2 infection : a systematic review
(Elsevier, 2022)Containing the COVID-19 pandemic requires rapidly identifying infected individuals. Subtle changes in physiological parameters (such as heart rate, respiratory rate, and skin temperature), discernible by wearable devices, ... -
Variations in risks from smoking between high-income, middle-income, and low-income countries: an analysis of data from 179 000 participants from 63 countries
(Elsevier BV, 2022)Background Separate studies suggest that the risks from smoking might vary between high-income (HICs), middle- income (MICs), and low-income (LICs) countries, but this has not yet been systematically examined within a ... -
Lifestyle influences changes in fibrin clot properties over a 10-year period on a population level
(Georg Thieme Verlag, 2022)Case–control and observational studies have provided a plausible mechanistic link between clot structure and thrombosis. We aimed to identify lifestyle, demographic, biochemical, and genetic factors that influence changes ... -
Meaning making mechanisms in women survivors of childhood sexual abuse : a scoping review
(SAGE Publications, 2022)Childhood sexual abuse (CSA) is a complex and prevalent problem with devastating long-term consequences for survivors. Despite these consequences, some survivors seem to find a source of meaning and fulfillment throughout ... -
Protective immunity of plant-produced African horse sickness virus serotype 5 chimaeric virus-like particles (VLPs) and viral protein 2 (VP2) vaccines in IFNAR -/- mice
(Elsevier, 2022)Next generation vaccines have the capability to contribute to and revolutionise the veterinary vaccine industry. African horse sickness (AHS) is caused by an arbovirus infection and is characterised by respiratory distress ... -
Interpretive description of recreational therapy within thecurricula of selected healthcare professions in South Africa
(Taylor & Francis Ltd, 2022)In South Africa (SA), recreational therapy (RT)/therapeutic recreation(TR) as profession ended in June 1978 and currently remain sun recognized as a profession. Some of the existing health professions in SA may provide ... -
Leisure education and recreation participation : a niche for recreational therapy in South Africa
(Taylor and Francis Ltd., 2022)The practice of Recreational Therapy/Therapeutic recreation (RT/TR) in South Africa (SA) is currently unrecognized, and whether some of the existing health professions in SA are providing services like those of RT/TR, as ... -
Factors inhibiting implementation of Integrated Management of Childhood Illnesses (IMCI) in primary health care (PHC) facilities in Mafikeng subdistrict.
(Elsevier, 2019)Background: The main objective of the Integrated Management of Childhood Illnesses (IMCI) strategy was to reduce child mortality and morbidity, which are associated with major childhood illnesses. IMCI offers a comprehensive ... -
Comparison of body mass index and fat percentage criteria classification of 7-13 year-old rural boys in South Africa
(BMC, 2020)Abstract Background: The aim of this paper was to investigate whether BMI and fat percentage classification criteria, would classify a sample of 7–13 year old boys from a rural background in similar nutritional ... -
Methylene blue analogues: in vitro antimicrobial minimum inhibitory concentrations and in silico pharmacophore modelling
(Elsevier, 2020)It has been shown that methylene blue has antimicrobial properties although few studies have determined its minimum inhibitory concentration (MIC), which is the gold standard used to measure antimicrobial activity. The ... -
Metronidazole-conjugates: a comprehensive review of recent developments towards synthesis and medicinal perspective
(Elsevier, 2020)Nitroimidazoles based compounds remain a hot topic of research in medicinal chemistry due to their numerous biological activities. Moreover, many clinical candidates based on this chemical core have been reported to be ... -
COVID-19 across Africa: epidemiologic heterogeneity and necessity of contextually relevant transmission models and intervention strategies
(American College of Physicians, 2020)Coronavirus disease 2019 (COVID-19) has rapidly emerged as a global public health threat with epicenters in regions of China, parts of Europe, and larger urban centers across North America (1). By comparison, population-level ... -
Towards a methodology for online VR application testing
(IEEE, 2020)Performing online testing for applications is a common practice in business, but for research without much control over the participants it is unknown as to what this process should look like and what could be possible ... -
The rat hippocampal gliovascular system following one week vortioxetine and fluoxetine
(Elsevier, 2020)We have previously reported that vortioxetine, unlike the selective serotonin reuptake inhibitor fluoxetine, produces a rapid increase of dendritic spine number and Brain Derived Neurotrophic Factor (BDNF)-associated ... -
Reflections on the OECD guidelines for in vitro skin absorption studies
(Elsevier, 2020)At the 8th conference of Occupational and Environmental Exposure of the Skin to Chemicals (OEESC) (16–18 September 2019) in Dublin, Ireland, several researchers performing skin permeation assays convened to discuss in vitro ... -
2020 International Society of Hypertension global hypertension practice guidelines - lifestyle modification. Reply
(Wolters Kluwer, 2020)The 2020 ISH Global Hypertension Practice Guidelines [1] include a detailed list of lifestyle modifications with varying levels of evidence for the reduction of blood pressure and cardiovascular risk. We listed some novel ... -
Diet and sedentary behaviour in relation to mortality in US adults with a cardiovascular condition: results from the National Health and Nutrition Examination Survey linked to the US mortality registry
(Cambridge Univ Pess, 2020)CVD is the most common chronic condition and the highest cause of mortality in the USA. The aim of the present work was to investigate diet and sedentary behaviour in relation to mortality in US CVD survivors. The National ... -
Synthesis and in vitro antileishmanial efficacy of benzyl analogues of nifuroxazide
(Wiley, 2020)Leishmaniasis is a vector‐borne parasitic disease that mostly affects populations in tropical and subtropical countries. There is currently no vaccine to protect against and only a handful of drugs are available to treat ... -
C3 amino-substituted chalcone derivative with selective adenosine rA1 receptor affinity in the micromolar range
(Springer, 2020)To identify novel adenosine receptor (AR) ligands based on the chalcone scaffold, herein the synthesis, characterization and in vitro and in silico evaluation of 33 chalcones (15–36 and 37–41) and structurally related ... -
Coexisting conditions among children and adolescents with cancer in a section of the South African private health sector: perspectives from drug utilization data
(Atlantis Press, 2020)Coexisting conditions are relatively common in children with cancer, however, there is a paucity of information on the prevalence of coexisting conditions in children with cancer in South Africa. This cross-sectional study ...
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