Browsing Faculty of Health Sciences by Author "645663d0-f860-46de-aa21-dc480cc1fd53"
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Antioxidant enzyme activity is associated with blood pressure and carotid intima media thickness in black men and women: the SABPA study
Van Zyl, Caitlynd; Huisman, Hugo W.; Mels, Catharina M.C. (Elsevier, 2016)In the urbanized black population of South Africa, oxidative stress may play a crucial role in the development of hypertension. Since oxidative stress may result from impaired antioxidant capacity we aimed to investigate ... -
The association of endothelin-1 with markers of oxidative stress in a biethnic South African cohort: the SABPA study
Du Plooy, Christine Susara; Mels, Catharina Martha Cornelia; Huisman, Hugo Willem; Kruger, Ruan (Springer Nature, 2017)Both endothelin-1 and oxidative stress have important roles in the development of cardiovascular diseases such as hypertension and atherosclerosis. Limited information is available on the interaction between oxidative ... -
Attenuated IGF-1 predicts all-cause and cardiovascular mortality in a Black population: a five-year prospective study
Schutte, Aletta E.; Conti, Elena; Mels, Catharina M.C.; Smith, Wayne; Kruger, Ruan; Botha, Shani; Huisman, Hugo W. (Sage Publications Ltd, 2016)Background: Inconsistent findings are reported on whether insulin-like growth factor-1 (IGF-1) is protective or harmful in predicting hypertension, carotid wall thickness and mortality. We determined the five-year ... -
Cardiovascular function is not associated with creatine kinase activity in a black African population: the SABPA study
Mels, Catharina M.C.; Van Zyl, Caitlynd; Huisman, Hugo W. (Biomed Central Ltd, 2016)Background: Higher creatine kinase (CK) activity is associated with the development of cardiovascular disease in black African populations. We compared CK activity and investigated associations of blood pressure with CK ... -
Inflammation as possible mediator for the relationship between lung and artirial function
Van Rooyen, Yolandi; Schutte, Aletta E.; Huisman, Hugo W.; Eloff, Fritz C.; Du Plessis, Johan L.; Kruger, Annamarie; Van Rooyen, Johannes M. (Springer, 2016)Introduction Reduced lung function is associated with a risk for the development of cardiovascular disease. This association may be due to chronic inflammation which is often present in those with reduced lung ... -
Lung function, inflammation and cardiovascular mortality in Africans
Breet, Yolandi; Schutte, Aletta E.; Huisman, Hugo W.; Eloff, Frederik C.; Du, Plessis Johannes L.; Kruger, Annamarie; Van Rooyen, Johannes M. (Wiley, 2016)Background The link between impaired lung function and cardiovascular outcome is well established in European and American populations. It is possible that this association may be driven by a systemic spillover of ... -
Masked hypertension and its associated cardiovascular risk in young individuals: the African-PREDICT study
Thompson, Jane E.S.; Smith, Wayne; Ware, Lisa J.; Mels, Catharina M.C.; Van Rooyen, Johannes M.; Huisman, Hugo W.; Malan, Leoné; Malan, Nicolaas T.; Lammertyn, Leandi; Schutte, Aletta E. (Springer Nature, 2016)Hypertension prevalence is increasing globally, yet little is known about the occurrence of masked hypertension (MHT) in young, sub-Saharan African adults, and how it relates to elevated cardiovascular risk. The African-PREDICT ... -
Quantification of systemic renin-angiotensin system peptides of hypertensive black and white African men established from the RAS-Fingerprint
Van Rooyen, J.M.; Huisman, H.W.; Mels, C.M.C.; Kruger, R.; Malan, L.; Botha, S.; Lammertyn, L.; Gafane, L.; Schutte, A.E. (Sage, 2016)Objective: The objective of this study was to make use of a quantitative and qualitative approach comparing the systemic renin-angiotensin system (RAS) of hypertensive black and white African men by using RAS equilibrium ...