Browsing Faculty of Health Sciences by Subject "Inflammation"
Now showing items 1-10 of 21
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Bioavailable IGF-1 and its relation to the metabolic syndrome in a bi-ethnic population of men and women
(Georg Thieme Verlag, 2016)Insulin-like growth factor 1 (IGF-1), an insulin sensitivity and vasculoprotective factor, associates negatively with the metabolic syndrome. However, IGF-1 is reduced by factors such as inflammation, oxidative stress and ... -
Change in renin, cardiovascular and inflammatory markers over three years in a black and white population: the SABPA study
(BioMed Central, 2017)Background: To investigate if percentage change (%Δ) in renin over a 3 year follow-up is associated with %Δ in cardiovascular and inflammatory markers in a low renin bi-ethnic group. Methods: Blood pressure, active renin, ... -
Defensive coping and essential amino acid markers as possible predictors for structural vascular disease in an African and Caucasian male cohort: the SABPA study
(Wiley, 2017)Defensive coping (DefS), oxidative stress, inflammation, and related amino acids (phenylalanine [Phe] and tyrosine [Tyr]) have been implicated in cardiovascular disease. This study assessed whether inflammation, oxidative ... -
Depressive symptoms and sub-clinical atherosclerosis in Africans: role of metabolic syndrome, inflammation and sympathoadrenal function
(Elsevier, 2011)Depressive symptoms have been consistently associated with sub-clinical atherosclerosis and future risk of coronary heart disease events. However, the pathways linking depression and coronary atherosclerosis are poorly ... -
Distinct inflammatory mediator patterns in young black and white adults: the African-predict study
(Elsevier, 2020)Objective Inflammatory mediators have been implicated in the early stages of cardiovascular disease development, including hypertension. Since global reports reflect a higher hypertension prevalence in black than white ... -
An ethnic comparison of arginine dimethylation and cardiometabolic factors in healthy black and white youth: the ASOS and African-PREDICT studies
(MDPI, 2020)Proteinic arginine dimethylation (PADiMe) is a major post-translational modification. Proteolysis of asymmetric and symmetric PADiMe products releases asymmetric dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA), ... -
Extracellular matrix biomarker, Fibulin–1 and Its association with Soluble uPAR in a Bi-ethnic South African population: the SAfrEIC study
(Elsevier, 2015)Background Fibulin-1 and soluble urokinase-type plasminogen activator receptor (suPAR) emerged as mediators in the development of sclerotic disease. SuPAR along with C-reactive protein (CRP) and albumin delineate ... -
Garcinia mangostana Linn displays antidepressant-like and pro-cognitive effects in a genetic animal model of depression: a bio-behavioral study in the Flinders Sensitive Line rat
(Springer, 2018)There is abundant evidence for both disorganized redox balance and cognitive deficits in major depressive disorder (MDD). Garcinia mangostana Linn (GM) has anti-oxidant activity. We studied the antidepressant-like and ... -
Growth differentiating factor-15 and its association with traditional cardiovascular risk factors: the African-PREDICT study.
(Elsevier, 2020)Background and aims Growth differentiating factor-15 (GDF-15) is a stress-induced and cardio-protective cytokine, reported to be influenced by a number of cardiovascular risk factors. In older adults, GDF-15 associated ... -
Hyperpulsatile pressure, systemic inflammation and cardiac stress are associated with cardiac wall remodeling in an African male cohort: the SABPA study
(Nature, 2016)Inflammation may contribute to an increase in cardiac wall stress through pathways related to cardiac remodeling. Cardiac remodeling is characterized by myocyte hypertrophy, myocyte death and modifications of the extracellular ...