Now showing items 1-3 of 3

    • In vitro anti-cancer effects of artemisone nano-vesicular formulations on melanoma cells 

      Dwivedi, Anupma; Mazumder, Anisha; Du Plessis, Lissinda; Du Preez, Jan L.; Haynes, Richard K.; Du Plessis, Jeanetta (Elsevier, 2015)
      Artemisone is a 10-amino-artemisinin derivative that is markedly superior in vitro and in vivo to current artemisinins against malaria and also possesses antitumor activity. In seeking to capitalise on the last property, ...
    • In vitro skin permeation of artemisone and its nano-vesicular formulations 

      Dwivedi, Anupma; Mazumder, Anisha; Fox, Lizelle T.; Brümmer, Alicia; Gerber, Minja; Du Preez, Jan L.; Haynes, Richard K.; Du Plessis, Jeanetta (Elsevier, 2016)
      The artemisinin derivative artemisone has antitumor activity. In particular when encapsulated in solid lipid nanoparticles (SLNs) and niosomes, it is active against human melanoma A-375 cells, although such formulations ...
    • Topical delivery of Withania somnifera crude extracts in niosomes and solid lipid nanoparticles 

      Chinembiri, Tawona N.; Gerber, Minja; Du Plessis, Lissinda H.; Du Preez, Jan L.; Hamman, Josias H.; Du Plessis, Jeanetta (Medknow, 2017)
      Background: Withania somnifera is a medicinal plant native to India and is known to have anticancer properties. It has been investigated for its anti-melanoma properties, and since melanoma presents on the skin, it is ...