Browsing Faculty of Health Sciences by Subject "Atherosclerosis"
Now showing items 1-6 of 6
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Asymmetric dimethylarginine and l-homoarginine prospectively relate to carotid wall thickness in a South African cohort
(Springer, 2020)Background and aims The L-arginine derivatives asymmetric (ADMA) and symmetric dimethylarginine (SDMA), as well as L-homoarginine may have opposing effects in the pathogenesis of atherosclerosis. We aimed to investigate ... -
Attenuated IGF-1 predicts all-cause and cardiovascular mortality in a Black population: a five-year prospective study
(Sage Publications Ltd, 2016)Background: Inconsistent findings are reported on whether insulin-like growth factor-1 (IGF-1) is protective or harmful in predicting hypertension, carotid wall thickness and mortality. We determined the five-year ... -
Carotid cross-sectional wall area is significantly associated with serum leptin levels, independent of body mass index: the SABPA studyent of body mass index: the SABPA study
(Japanese Society of HypertensionNature Publishing Group, 2012)Hypertension and obesity are serious health burdens in sub-Saharan Africa. Urbanized Africans seem to be more susceptible to the development of these diseases than Caucasians. Current research suggests that leptin may be ... -
An ethnic comparison of arginine dimethylation and cardiometabolic factors in healthy black and white youth: the ASOS and African-PREDICT studies
(MDPI, 2020)Proteinic arginine dimethylation (PADiMe) is a major post-translational modification. Proteolysis of asymmetric and symmetric PADiMe products releases asymmetric dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA), ... -
Leptin and the vasculature in young adults: the African‐PREDICT study
(Wiley, 2019)Background and aim Information regarding the effect of leptin on the vasculature in young healthy adults at risk for cardiovascular disease development is limited. We therefore examined the associations between measures ... -
Selenium and large artery structure and function: a 10-year prospective study
(Springer, 2019)Purpose Despite selenium’s beneficial effects in counteracting oxidative stress, inflammation, and vascular endothelial dysfunction, controversial results exist regarding the long-term associations between selenium and ...