Now showing items 1-2 of 2

    • In vitro anti-trypanosomal activities of indanone-based chalcones 

      Beteck, Richard M.; Legoabe, Lesetja J.; Isaacs, Michelle; Hoppe, Heinrich C. (Thieme, 2018)
      Human African trypanosomiasis is a neglected infectious disease that affects mostly people living in the rural areas of Africa. Current treatment options are limited to just four drugs that have been in use of four to nine ...
    • Indanones as high-potency reversible inhibitors of monoamine oxidase 

      Mostert, Samantha; Petzer, Anél; Petzer, Jacobus P. (Wiley, 2015)
      Recent reports document that α-tetralone (3,4-dihydro-2H-naphthalen-1-one) is an appropriate scaffold for the design of high-potency monoamine oxidase (MAO) inhibitors. Based on the structural similarity between α-tetralone ...