Browsing Faculty of Health Sciences by Subject "Insulin"
Now showing items 1-4 of 4
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Development and evaluation of a double-phase multiple-unit dosage form for enhanced insulin intestinal delivery
(Bentham Science, 2018)Background: The oral route is the most preferred route of administration for selfmedication, but poor membrane permeability and pre-systemic degradation are key challenges that need to be addressed. Objective: The purpose ... -
Eudragit® L100/N-trimethylchitosan chloride microspheres for oral insulin delivery
(MDPI, 2013)Effective oral delivery of protein and peptide drugs remains an active topic in scientific research. In this study, matrix type microspheres were prepared with Eudragit® L100 containing N-trimethylchitosan chloride to ... -
Gastrointestinal region specific insulin permeation enhancement by Aloe vera gel
(Bentham Science, 2020)Background: The oral administration route is still the most preferred by patients for drug treatment, but is unfortunately not suitable for all drug compounds. For example, protein and peptide drugs (e.g. insulin) are ... -
The microbial metabolite indole-3-propionic acid improves glucose metabolism in rats, but does not affect behaviour
(Taylor & Francis, 2018)Context: We have previously shown that an antidepressant-like effect of probiotics in rats was associated with a higher plasma level of the microbial tryptophan metabolite indole-3-propionic acid (IPA). Objective: We ...