Now showing items 1-3 of 3

    • Effects of protein binding on the biodistribution of PEGylated PLGA nanoparticles post oral administration 

      Hayeshi, Rose; Kalombo, Lonji; Ramalapa, Bathabile; Semete, Boitumelo; Booysen, Laetitia; Swai, Hulda S.; Hayeshi, Rose; Kalombo, Lonji; Ramalapa, Bathabile; Semete, Boitumelo; Booysen, Laetitia; Swai, Hulda S. (Elsevier, 2012)
      The surface of nanoparticles is often functionalised with polymeric surfactants, in order to increase systemic circulation time. This has been investigated mainly for intravenously administered nanoparticles. This study ...
    • In vivo evaluation of the biodistribution and safety of PLGA nanoparticles as drug delivery systems 

      Semete, Boitumelo; Booysen, Laetitia; Lemmer, Yolandy; Kalombo, Lonji; Katata, Lebogang; Verschoor, Jan; Swai, Hulda S.; Semete, Boitumelo; Booysen, Laetitia; Lemmer, Yolandy; Kalombo, Lonji; Katata, Lebogang; Verschoor, Jan; Swai, Hulda S. (Elsevier, 2010)
      The remarkable physicochemical properties of particles in the nanometer range have been proven to address many challenges in the field of science. However, the possible toxic effects of these particles have raised some ...
    • Permeation of PLGA nanoparticles across different in vitro models 

      Nkabinde, Lindiwe A.; Hamman, Josias H.; Shoba-Zikhali, Lungile N.N.; Semete-Makokotlela, Boitumelo; Kalombo, Lonji; Nkabinde, Lindiwe A.; Hamman, Josias H.; Shoba-Zikhali, Lungile N.N.; Semete-Makokotlela, Boitumelo; Kalombo, Lonji (Bentham Science, 2012)
      Many drug delivery systems have indicated improvement in delivery of various drug molecules and among these biodegradable and biocompatible polymers such as poly(D,L-lactide-co-glycolide) (PLGA) have been shown to enhance ...