Browsing Faculty of Health Sciences by Subject "Melanoma"

Now showing items 1-5 of 5

    • Anti-melanoma activities of artemisone and prenylated amino-artemisinins in combination with known anticancer drugs 

      Wong, Ho Ning; Lewies, Angélique; Haigh, Michaela; Viljoen, Joe M.; Wentzel, Johannes F.; Haynes, Richard K.; Du Plessis, Lissinda H. (Frontiers Media, 2020)
      The most frequently occurring cancers are those of the skin, with melanoma being the leading cause of death due to skin cancer. Breakthroughs in chemotherapy have been achieved in certain cases, though only marginal advances ...

    • The antimicrobial peptide nisin Z induces selective toxicity and apoptotic cell death in cultured melanoma cells 

      Lewies, Angélique; Wentzel, Johannes Frederik; Van Dyk, Hayley; Du Plessis, Lissinda Hester (Elsevier, 2018)
      Reprogramming of cellular metabolism is now considered one of the hallmarks of cancer. Most malignant cells Reprogramming of cellular metabolism is now considered one of the hallmarks of cancer. Most malignant cells present ...

    • In vitro anti-cancer effects of artemisone nano-vesicular formulations on melanoma cells 

      Dwivedi, Anupma; Mazumder, Anisha; Du Plessis, Lissinda; Du Preez, Jan L.; Haynes, Richard K.; Du Plessis, Jeanetta (Elsevier, 2015)
      Artemisone is a 10-amino-artemisinin derivative that is markedly superior in vitro and in vivo to current artemisinins against malaria and also possesses antitumor activity. In seeking to capitalise on the last property, ...

    • In vitro skin permeation of artemisone and its nano-vesicular formulations 

      Dwivedi, Anupma; Mazumder, Anisha; Fox, Lizelle T.; Brümmer, Alicia; Gerber, Minja; Du Preez, Jan L.; Haynes, Richard K.; Du Plessis, Jeanetta (Elsevier, 2016)
      The artemisinin derivative artemisone has antitumor activity. In particular when encapsulated in solid lipid nanoparticles (SLNs) and niosomes, it is active against human melanoma A-375 cells, although such formulations ...

    • Review of natural compounds for potential skin cancer treatment 

      Chinembiri, Tawona N.; Du Plessis, Lissinda H.; Gerber, Minja; Hamman, Josias H.; Du Plessis, Jeanetta (MDPI, 2014)
      Most anti-cancer drugs are derived from natural resources such as marine, microbial and botanical sources. Cutaneous malignant melanoma is the most aggressive form of skin cancer, with a high mortality rate. Various ...