Now showing items 1-4 of 4

    • Topical and transdermal delivery of L-carnitine 

      Fox, L.T.; Gerber, M.; Grobler, A.; Du Preez, J.L.; Du Plessis, J.; Fox, L.T.; Gerber, M.; Grobler, A.; Du Preez, J.L.; Du Plessis, J. (Karger, 2011)
      Background: The two types of skin aging (intrinsic and extrinsic) share important molecular features, while having distinct differences on the macromolecular level: both lead to increased production of reactive oxygen ...
    • Topical delivery of acyclovir and ketoconazole 

      Jacobs, Gerda A.; Gerber, Minja; Malan, Maides M.; Du Preez, Jan L.; Fox, Lizelle T.; Du Plessis, Jeanetta (Taylor & Francis, 2014)
      Context: Viral and fungal cutaneous manifestations are regularly encountered in immunocompromised HIV/AIDS individuals and can be treated by drugs such as acyclovir and ketoconazole, respectively. Objective: The aim of ...
    • Topical delivery of artemisone, clofazimine and decoquinate encapsulated in vesicles and their in vitro efficacy against Mycobacterium tuberculosis 

      Van Zyl, Lindi; Viljoen, Joe M.; Haynes, Richard k.; Aucamp, Marique; Du Plessis, Jeanetta (Springer, 2019)
      Vesicles are widely investigated as carrier systems for active pharmaceutical ingredients (APIs). For topical delivery, they are especially effective since they create a “depot-effect” thereby concentrating the APIs in the ...
    • Topical delivery of roxithromycin solid-state forms entrapped in vesicles 

      Csongradi, Candice; Du Plessis, Jeanetta; Aucamp, Marique Elizabeth; Gerber, Minja (Elsevier, 2017)
      Recently, considerable interest developed in using newer/improved antibiotics for the treatment of Acne vulgaris. During this study, different roxithromycin solid-state forms (i.e. crystalline and amorphous) were encapsulated ...