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8-Oxo-7,8-dihydro-2’-deoxyguanosine, reactive oxygen species and ambulatory blood pressure in African and Caucasian men: the SABPA study
(Taylor & Francis, 2014)
Various studies indicate a relationship between increased oxidative stress and hypertension, resulting in increased DNA damage and consequent excretion of 8-oxo-7,8-dihydro-2’-deoxyguanosine (8-oxodG). The aim of this study ...
Compromised bioavailable IGF-1 of black men relates favourably to ambulatory blood pressure: the SABPA study
(Elsevier, 2014)
Objectives
Insulin-like growth factor-1 (IGF-1) has potent endothelial-protective, anti-platelet and anti-thrombotic activities, and also exerts mitogenic and proliferatory actions on vascular smooth muscle cells. Conflicting ...
Urinary albumin excretion from spot urine samples predict all-cause and stroke mortality in Africans
(Oxford University Press, 2014)
BACKGROUND: Increased urinary albumin excretion reflects general vascular damage and predicts adverse cardiovascular and renal outcomes. Albuminuria can be determined from easily collected spot urine samples, especially ...
Evaluation of waist-to-height ratio to predict 5 year cardiometabolic risk in sub-Saharan African adults
(Open Access, 2014)
Background and aims Simple, low-cost central obesity measures may help identify individuals with increased cardiometabolic disease risk, although it is unclear which measures perform best in African adults. We aimed to: ...