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Cardiometabolic markers to identify cardiovascular disease risk in HIV-infected black South Africans
(2014)
Background.
The prevalence of HIV is the highest in sub-Saharan Africa; South Africa (SA) is one of the most affected countries with the
highest number of adults living with HIV infection in the world. Besides ...
8-Oxo-7,8-dihydro-2’-deoxyguanosine, reactive oxygen species and ambulatory blood pressure in African and Caucasian men: the SABPA study
(Taylor & Francis, 2014)
Various studies indicate a relationship between increased oxidative stress and hypertension, resulting in increased DNA damage and consequent excretion of 8-oxo-7,8-dihydro-2’-deoxyguanosine (8-oxodG). The aim of this study ...
Compromised bioavailable IGF-1 of black men relates favourably to ambulatory blood pressure: the SABPA study
(Elsevier, 2014)
Objectives
Insulin-like growth factor-1 (IGF-1) has potent endothelial-protective, anti-platelet and anti-thrombotic activities, and also exerts mitogenic and proliferatory actions on vascular smooth muscle cells. Conflicting ...
Attenuated NOx responses and myocardial ischemia, a possible risk for structural vascular disease in African men: the SABPA study
(Nature Publishing Group, 2014)
Chronically elevated blood pressure has been associated with impaired NO-mediated vasodilation and structural vascular disease risk. This study aimed to determine whether significant associations exist regarding NO metabolite ...
Chronic distress and acute vascular stress responses associated with ambulatory blood pressure in low-testosterone African men: the SABPA Study
(Nature Publishing Group, 2014)
It is known that low testosterone (T) and high cortisol levels are associated with hypertension as well as with chronic stress, linking stress with elevated blood pressure (BP). However, the association between acute ...
Leukocyte telomere length and hemostatic factors in a South African cohort: the SABPA study
(Wiley, 2014)
Background
Incident atherothrombotic disease is predicted by leukocyte telomere length, a marker of biological age, and hemostatic factor levels, indicating a hypercoagulable state. We hypothesized that shorter telomeres ...
Examining waist and neck circumferences as screening tools for metabolic syndrome in a sub-Saharan Caucasian cohort at three year follow-up: the SABPA prospective cohort
(MedPharm Publications, 2014)
Objectives: Waist circumference (WC) cut-off points specific to sub-Saharan Caucasians do not exist with which to identify metabolic syndrome. Neck circumference (NC), as an additional measure, was previously found to be ...