Now showing items 1-10 of 32
Global, regional, and national life expectancy, all–cause mortality, and cause–specifi c mortality for 249 causes of death, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015
Background Improving survival and extending the longevity of life for all populations requires timely, robust evidence on local mortality levels and trends. The Global Burden of Disease 2015 Study (GBD 2015) provides ...
Is 24-hour central blood pressure superior to 24-hour brachial blood pressure for predicting organ damage?
(American Heart Association, 2017)
Global, regional, and national disability-adjusted life-years (DALYs) for 315 diseases and injuries and healthy life expectancy (HALE), 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015
Background Healthy life expectancy (HALE) and disability-adjusted life-years (DALYs) provide summary measures of health across geographies and time that can inform assessments of epidemiological patterns ...
Quantification of systemic renin-angiotensin system peptides of hypertensive black and white African men established from the RAS-Fingerprint
Objective: The objective of this study was to make use of a quantitative and qualitative approach comparing the systemic renin-angiotensin system (RAS) of hypertensive black and white African men by using RAS equilibrium ...
Plasma renin and cardiovascular responses to the cold pressor test differ in black and white populations: the SABPA study
(Springer Nature, 2016)
Low plasma renin levels and augmented cardiovascular reactivity to stress are common in blacks and have been linked to the development of hypertension in this population. We (i) compared cardiovascular and plasma renin ...
Alcohol intake, hypertension development and mortality in black South Africans
(Sage Publishing, 2016)
Background: Excessive alcohol intake is a risk factor for cardiovascular disease (CVD) and predicts cardiovascular and all-cause mortality. We determined which alcohol marker (self-reported alcohol intake, gamma-glutamy ...
Nitric oxide synthesis capacity, ambulatory blood pressure and end organ damage in a black and white population: the SABPA study
Nitric oxide (NO) synthesis capacity is determined by the availability of substrate(s) such as l-arginine and the influence of nitric oxide synthase (NOS) inhibitors, asymmetric dimethylarginine (ADMA) and symmetric ...
Masked hypertension and its associated cardiovascular risk in young individuals: the African-PREDICT study
(Springer Nature, 2016)
Hypertension prevalence is increasing globally, yet little is known about the occurrence of masked hypertension (MHT) in young, sub-Saharan African adults, and how it relates to elevated cardiovascular risk. The African-PREDICT ...
Masked hypertension in low-income South African adults
While South Africa has one of the highest hypertension rates globally, there are few data on masked hypertension (MHT) and white-coat hypertension (WCHT). This study measured the frequency of MHT and WCHT in low-income ...
Lung function, inflammation and cardiovascular mortality in Africans
Background The link between impaired lung function and cardiovascular outcome is well established in European and American populations. It is possible that this association may be driven by a systemic spillover of ...