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Masked hypertension and its associated cardiovascular risk in young individuals: the African-PREDICT study
(Springer Nature, 2016)
Hypertension prevalence is increasing globally, yet little is known about the occurrence of masked hypertension (MHT) in young, sub-Saharan African adults, and how it relates to elevated cardiovascular risk. The African-PREDICT ...
Chronic defensiveness and neuroendocrine dysfunction reflect a novel cardiac troponin T cut point: the SABPA study
(Elsevier, 2017)
Background
Sympatho-adrenal responses are activated as an innate defense coping (DefS) mechanism during emotional stress. Whether these sympatho-adrenal responses drive cardiac troponin T (cTnT) increases are unknown. ...
Prognostic significance of dipping in older hypertensive patients
(Taylor & Francis, 2015)
Background and aims. Arterial hypertension doubles the risk of coronary heart disease, heart and kidney failure, and peripheral arterial disease. Less variation in diurnal ambulatory blood pressure monitoring (ABPM) patterns ...
Retinal vessel caliber and its relationship with nocturnal blood pressure dipping status: the SABPA study
(Springer Nature, 2016)
Adverse changes in retinal microvasculature caliber are associated with incident hypertension, coronary heart disease and stroke. The absence of a nocturnal dipping in arterial pressure may induce changes throughout the ...
Defensive coping and essential amino acid markers as possible predictors for structural vascular disease in an African and Caucasian male cohort: the SABPA study
(Wiley, 2017)
Defensive coping (DefS), oxidative stress, inflammation, and related amino acids (phenylalanine [Phe] and tyrosine [Tyr]) have been implicated in cardiovascular disease. This study assessed whether inflammation, oxidative ...
The protective role of oestradiol against silent myocardial ischemia and hypertension risk in South African men: the SABPA study
(Elsevier, 2017)
Background
Oestradiol has a protective effect on coronary artery health in women but the effect it has on men, is controversial. A translational approach was followed to assess whether sex hormone levels are associated ...
The defense response and alcohol intake: a coronary artery disease risk: the SABPA study
(Taylor & Francis, 2016)
The behavioral defense coping response (DefS) as a measure of coping with emotional stress may increase alcohol intake (gamma glutamyl transferase (γGT)), the risk for coronary artery disease (CAD) and insulin sensitivity ...
Association between objectively measured physical activity, chronic stress and leukocyte telomere length
(Edizioni Minerva Medica, 2017)
BACKGROUND: Physical activity (PA ) attenuates chronic stress and age-related and cardiovascular disease risks, whereby potentially slowing
telomere shortening. We aimed to study the association between seven-day objectively ...
The contribution of the C-824T tyrosine hydroxylase polymorphism to the prevalence of hypertension in a South African cohort: the SABPA study
(Taylor & Francis, 2013)
The C-824T single nucleotide polymorphism in the promoter region of the tyrosine hydroxylase gene has been associated with hypertension. It is well documented that African South Africans exhibit a higher prevalence of ...
Fibrosis and coronary perfusion: a cardiovascular disease risk in an African male cohort: the SABPA study
(Taylor & Francis, 2016)
Low-grade inflammation has been correlated with risk factors of cardiovascular diseases (CVD). Whether the pro-inflammatory and thrombotic ratio (fibrosis) may contribute to CVD is not known. We therefore aimed to assess ...